共 2471 条结果
Scientific reports
2021
Yang M, Liu M, Cheng J, Wang H
Biosensors have been widely used in various fields such as food industry, environmental testing and medical testing for their high sensitivity. However, current fabric...
Nature communications
2021
Bell GRR, Rincón E, Akdoğan E, Collins SR
During chemotaxis, neutrophils use cell surface G Protein Coupled Receptors to detect chemoattractant gradients. The downstream signaling system is wired with multiple...
The Journal of biological chemistry
2021
Krantz S, Kim YM, Srivastava S, Leasure JW 等 7 人
Pluripotent stem cells are known to shift their mitochondrial metabolism upon differentiation, but the mechanisms underlying such metabolic rewiring are not fully unde...
ACS sensors
2021
Vongsouthi V, Whitfield JH, Unichenko P, Mitchell JA 等 13 人
Solute-binding proteins (SBPs) have evolved to balance the demands of ligand affinity, thermostability, and conformational change to accomplish diverse functions in sm...
The Analyst
2021
Mohamed A, Walsh R, Cherif M, Hafez HA 等 8 人
We demonstrate the rapid and highly sensitive detection of a small molecule, microcystin-LR (MC-LR) toxin using an aptasensor based on a terahertz (THz) emission techn...
Frontiers in bioengineering and biotechnology
2021
Zhu Z, Geng Y, Wang Y, Liu K 等 10 人
Microfluidic devices in combination with fluorescent microscopy offer high-resolution and high-content platforms to study single-cell morphology, behavior and dynamic ...
Frontiers in bioengineering and biotechnology
2021
Yang J, Johnson CH
Sensitive detection of biological events is a goal for the design and characterization of sensors that can be used in vitro and in vivo. One important second messenger...
Frontiers in microbiology
2021
Materials (Basel, Switzerland)
2021
Fritea L, Banica F, Costea TO, Moldovan L 等 7 人
Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small...
Sensors (Basel, Switzerland)
2021
Yu X, Zhang S, Guo W, Li B 等 8 人
In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) bio...
International journal of molecular sciences
2021
Yasuda K, Nishikawa M, Mano H, Takano M 等 7 人
We have developed an in vitro system to easily examine the affinity for vitamin D receptor (VDR) and CYP24A1-mediated metabolism as two methods of assessing vitamin D ...
Scientific reports
2021
Bekmurzayeva A, Ashikbayeva Z, Myrkhiyeva Z, Nugmanova A 等 7 人
Frontiers in cellular and infection microbiology
2021
Ruiz P, Sepulveda D, Vidal JM, Romero R 等 11 人
Piscirickettsia salmonis is the etiological agent of piscirickettsiosis, the most prevalent disease in salmonid species in Chilean salmonids farms. Many bacteria produ...
ACS sensors
2021
Hussein HA, Kandeil A, Gomaa M, Mohamed El Nashar R 等 6 人
Due to the current global SARS-CoV-2 pandemic, rapid and accurate diagnostic tools are needed to prevent the spread of COVID-19 across the globe. An electrochemical se...
Analytica chimica acta
2021
Li MJ, An SY, Wu Y
Herein, a sensitive photoelectrochemical (PEC) biosensing platform was designed for quantitative monitoring of microRNA-141 (miRNA-141) based on Au nanoparticles@graph...
Analytica chimica acta
2021
Cheng S, Tu Z, Zheng S, Cheng X 等 8 人
A novel surface-enhanced Raman scattering (SERS)-based analytical technique was proposed to simultaneously detect two highly pathogenic bacteria, namely, Staphylococcu...
Analytical chemistry
2021
Yang F, Yao JS, Bu SC, Meng HY 等 7 人
Depending on the reaction between walkers and tracks, DNA walker is able to output signals continuously, which has attracted great attention from the bioanalytical com...
Analytical chemistry
2021
Hou YY, Xu J, Wang FT, Dong Z 等 9 人
The detection of microRNA (miRNA) in human serum has great significance for cancer prevention. Herein, a novel self-powered biosensing platform is developed, which eff...
ACS applied materials & interfaces
2021
Hu Q, Luo Y, Cao X, Chen Z 等 6 人
Sensing of ultralow-abundance nucleic acids (NAs) is integral to medical diagnostics and pathogen screening. We present herein an electrochemical method for the highly...
Analytical chemistry
2021
Li T, Liang Y, Li J, Yu Y 等 8 人
Tumor-derived exosomal miRNAs may have important functions in the onset and progression of cancers and are potential biomarkers for early diagnosis and prognosis monit...