共 1045 条结果
Molecular therapy. Methods & clinical development
2024
Yu L, Zhou Y, Shi XC, Wang GY 等 7 人
The viral genome titer is a crucial indicator for the clinical dosing, manufacturing, and analytical testing of recombinant adeno-associated virus (rAAV) gene therapy ...
Frontiers in plant science
2024
Kanapiya A, Amanbayeva U, Tulegenova Z, Abash A 等 7 人
Accurate and timely diagnosis of plant viral infections plays a key role in effective disease control and maintaining agricultural productivity. Recent advances in the...
ACS applied materials & interfaces
2024
Sun S, Chen J
Early cancer detection is crucial for effective treatment, but current methods have limitations. Novel biomaterials, such as hydrogels, offer promising alternatives fo...
Smart medicine
2024
Dadi S, Ocsoy I
In recent years, an encouraging breakthrough in the synthesis of immobilized enzymes in flower-shaped called "organic-inorganic hybrid nanoflowers (hNFs)" with greatly...
ACS measurement science au
2024
Bradley Z, Bhalla N
Accurately quantifying high analyte concentrations poses a challenge due to the common occurrence of the prozone or hook effect within sandwich assays utilized in plas...
Journal, genetic engineering & biotechnology
2024
Chinchilla-Cárdenas DJ, Cruz-Méndez JS, Petano-Duque JM, García RO 等 7 人
Aptamers are single-stranded oligonucleotide sequences capable of binding to specific ligands with high affinity. In this manner, they are like antibodies but have adv...
ACS applied materials & interfaces
2024
Garg M, Guo H, Maclam E, Zhanov E 等 10 人
The urgent need for real-time and noninvasive monitoring of health-associated biochemical parameters has motivated the development of wearable sweat sensors. Existing ...
STAR protocols
2024
Gökerküçük EB, Tramier M, Bertolin G
Here, we present a protocol to comprehensively quantify autophagy initiation using the readout of the microtubule associated protein 1 light chain 3 beta (LC3B) Förste...
Frontiers in cellular and infection microbiology
2024
Xiao F, Zhang Y, Xu W, Fu J 等 12 人
Mycoplasma pneumoniae is a significant pathogen responsible for community-acquired pneumonia, predominantly affecting children and adolescents. Here, we devised a rapi...
Kidney international
2024
Peti-Peterdi J, Gyarmati G
Yamamoto et al. developed an exciting technical advance to examine intracellular adenosine triphosphate levels with single-cell resolution in intact living kidney tiss...
PLOS digital health
2024
Wiebe M, Mackay M, Krishnan R, Tian J 等 15 人
INTRODUCTION: Common, consumer-grade biosensors mounted on fitness trackers and smartwatches can measure an array of biometrics that have potential utility in post-dis...
ACS applied materials & interfaces
2024
Chick S, Ataei Kachouei M, Knowlton K, Ali MA
Precision livestock farming utilizing advanced diagnostic tools, including biosensors, can play a key role in the management of livestock operations to improve the pro...
Analytical chemistry
2024
Glahn-Martínez B, Herranz S, Benito-Peña E, Orellana G 等 5 人
Cyclic olefin copolymers (COC; e.g., Zeonor, Topas, Arton, etc.) are materials with outstanding properties for developing point-of-care systems; however, the lack of f...
ACS sensors
2024
Erdoğan YC, Pilic J, Gottschalk B, Yiğit EN 等 13 人
In this study, we introduce a new separation of phases-based activity reporter of kinase (SPARK) for AMP-activated kinase (AMPK), named AMPK-SPARK, which reports the A...
ACS sensors
2024
Lubken RM, Lin YT, Haenen SRR, Bergkamp MH 等 7 人
Continuous biosensors measure concentration-time profiles of biomolecular substances in order to allow for comparisons of measurement data over long periods of time. T...
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
2024
Piedra FJ, Z RAR, Vélez MIZ, Murillo JPM 等 12 人
BACKGROUND/AIMS: Due to rapid metabolic and growth rates during the first two years of life, the nutritional needs of young children are high. Given the small portion ...
International journal for parasitology. Drugs and drug resistance
2024
Call DH, Adjei JA, Pilgrim R, Jeong JW 等 14 人
Kinetoplastid organisms, including Trypanosoma brucei, are a significant health burden in many tropical and semitropical countries. Much of their metabolism is poorly ...
Talanta
2024
Martínez-Periñán E, Palomares-Albarrán M, Toyos-Rodríguez C, Mateo-Martí E 等 9 人
The development of rapid, accurate, sensitive, and low-cost diagnostic methods for COVID-19 detection in real-time is the unique way to control infection sources and m...
Frontiers in chemistry
2024
Anisuzzaman S, Alimoradi N, Singappuli-Arachchige D, Banerjee S 等 9 人
Pyoverdines are iron-chelating siderophores employed by various pseudomonads to promote their growth in iron-limited environments, facilitating both beneficial and det...
ACS sensors
2024
Zhou J, Liu X, Zhang D, Ma G
Microtubule (MT) dynamics is tightly regulated by microtubule-associated proteins (MAPs) and various post-translational modifications (PTMs) of tubulin. Here, we intro...