Electrochemical Microneedles: Innovative Instruments in Health Care.
As a significant part of drug therapy, the mode of drug transport has attracted worldwide attention. Efficient drug delivery methods not only markedly improve the drug...
Design and Optimization of A Magneto-Plasmonic Sandwich Biosensor for Integration within Microfluidic Devices.
We designed a magneto-plasmonic biosensor for the immunodetection of antigens in minute sample volume. Both spherical gold nanoparticles (AuNP) and magnetic beads (MB)...
An Innovative Sandwich Type Biosensor towards Sensitive and Selective Monitoring of 2-Arachidonoylglycerol in Human Plasma Samples Using P(
In this work, 2-AG was successfully detected in human plasma samples using a new sandwich-type electrochemical immune device based on poly-β-cyclodextrin P(β-CD) funct...
Integration of Power-Free and Self-Contained Microfluidic Chip with Fiber Optic Particle Plasmon Resonance Aptasensor for Rapid Detection of SARS-CoV-2 Nucleocapsid Protein.
The global pandemic of COVID-19 has created an unrivalled need for sensitive and rapid point-of-care testing (POCT) methods for the detection of infectious viruses. Fo...
Dielectrophoresis: An Approach to Increase Sensitivity, Reduce Response Time and to Suppress Nonspecific Binding in Biosensors?
The performance of receptor-based biosensors is often limited by either diffusion of the analyte causing unreasonable long assay times or a lack of specificity limitin...
Ruthenium and Nickel Molybdate-Decorated 2D Porous Graphitic Carbon Nitrides for Highly Sensitive Cardiac Troponin Biosensor.
Two-dimensional (2D) layered materials functionalized with monometallic or bimetallic dopants are excellent materials to fabricate clinically useful biosensors. Herein...
Voltammetry Peak Tracking for Longer-Lasting and Reference-Electrode-Free Electrochemical Biosensors.
Electrochemical aptamer-based sensors offer reagent-free and continuous analyte measurement but often suffer from poor longevity and potential drift even with a robust...
A Smartphone-Based Biosensor for Non-Invasive Monitoring of Total Hemoglobin Concentration in Humans with High Accuracy.
In this paper, we propose a smartphone-based biosensor for detecting human total hemoglobin concentration in vivo with high accuracy. Compared to the existing biosenso...
Predicting Analyte Concentrations from Electrochemical Aptasensor Signals Using LSTM Recurrent Networks.
Nanomaterial-based aptasensors are useful devices capable of detecting small biological species. Determining suitable signal processing methods can improve the identif...
10.3390/biomedicines10102371
Regular cancer screening is critical for early cancer detection. Cancer screening tends to be burdensome, invasive, and expensive, especially for a comprehensive multi...
Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor.
The F-box protein beta-transducin repeat containing protein (β-TrCP) acts as a substrate adapter for the SCF E3 ubiquitin ligase complex, plays a crucial role in cell ...
Detection of Tropical Diseases Caused by Mosquitoes Using CRISPR-Based Biosensors.
Tropical diseases (TDs) are among the leading cause of mortality and fatality globally. The emergence and reemergence of TDs continue to challenge healthcare system. S...
Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA.
Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an importan...
Multiplexed Detection of Pathogens Using Solid-Phase Loop-Mediated Isothermal Amplification on a Supercritical Angle Fluorescence Array for Point-of-Care Applications.
Adaptations of new generation molecular techniques for multiplexed detection of pathogens are gaining interest in the field of point-of-care (POC) industry and onsite ...
Flexible Aggregation-Induced Emission-Active Hydrogel for On-Site Monitoring of Pesticide Degradation.
Benefiting from the stimuli-responsive property and powerful loading capacity, functionalized hydrogels are favorable for the fabrication of sensing devices. Herein, w...
Head-to-head comparison of the accuracy of saliva and nasal rapid antigen SARS-CoV-2 self-testing: cross-sectional study.
BACKGROUND: The diagnostic accuracy of unsupervised self-testing with rapid antigen diagnostic tests (Ag-RDTs) is mostly unknown. We studied the diagnostic accuracy of...
The Effect of a Dodecahedron-Shaped Structure on the Properties of an Enzyme.
In this research, the influence of a dodecahedron-shaped structure on the adsorption behavior of a horseradish peroxidase (HRP) enzyme glycoprotein onto mica substrate...
Multifunctional Core@Satellite Magnetic Particles for Magnetoresistive Biosensors.
Magnetoresistive (MR) biosensors combine distinctive features such as small size, low cost, good sensitivity, and propensity to be arrayed to perform multiplexed analy...
Label-free electrochemical immunosensor for highly sensitive COVID-19 spike protein detection.
The ongoing coronavirus pandemic responsible for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly increased the rate of global death and infect...
Recombinant protein G/Au nanoparticles/graphene oxide modified electrodes used as an electrochemical biosensor for
UNLABELLED: In this study, a simple label-free biosensor for Brucella was constructed, which based on the screen-printed carbon electrode (SPCE) modified by Recombinan...