Sustained wash-resistant receptor activation responses of GPR119 agonists.
G protein-coupled receptor 119 (GPR119) is involved in regulating metabolic homoeostasis, with GPR119 agonists targeted for the treatment of type-2 diabetes and obesit...
Diversity in the antibacterial potential of probiotic cultures Bacillus licheniformis MCC2514 and Bacillus licheniformis MCC2512.
The aim of the present study was to investigate the characteristic diversity and stability of antimicrobial compounds produced by two probiotic strains of Bacillus lic...
Evaluating the Thickness of Multivalent Glycopolymer Brushes for Lectin Binding.
Electrochemical impedance spectroscopy (EIS) is applied for investigating binding of lectins to multivalent glycopolymer brushes grafted from interdigital gold microel...
A self-referencing biosensor for real-time monitoring of physiological ATP transport in plant systems.
The objective of this study was to develop a self-referencing electrochemical biosensor for the direct measurement of ATP flux into the extracellular matrix by living ...
Kinetic studies of microfabricated biosensors using local adsorption strategy.
Micro/nano scale biosensors integrated with the local adsorption mask have been demonstrated to have a better limit of detection (LOD) and less sample consumptions. Ho...
Hemin/G-quadruplex-based DNAzyme concatamers for in situ amplified impedimetric sensing of copper(II) ion coupling with DNAzyme-catalyzed precipitation strategy.
A new signal-amplification strategy based on copper(II) (Cu(2+))-dependent DNAzyme was developed for sensitive impedimetric biosensing of Cu(2+) in aqueous solution by...
Diagnosing dengue virus infection: rapid tests and the role of micro/nanotechnologies.
UNLABELLED: Due to the progressive spread of the dengue virus and a rising incidence of dengue disease, its rapid diagnosis is important for developing countries and o...
Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.
Oxidative stress may contribute to cardiac ryanodine receptor (RyR2) dysfunction in heart failure (HF) and arrhythmias. Altered RyR2 domain-domain interaction (domain ...
A low cost color-based bacterial biosensor for measuring arsenic in groundwater.
Using arsenic (As) contaminated groundwater for drinking or irrigation has caused major health problems for humans around the world, raising a need to monitor As level...
A biosensing strategy for the rapid detection and classification of antibiotic resistance.
Antibiotic resistance (AR) poses an ever growing threat to global public health. Methods are urgently needed that simplify and accelerate the clinical detection and cl...
A doubly responsive probe for the detection of Cys4-tagged proteins.
Recombinant proteins bearing a tag are crucial tools for assessing protein location or function. Small tags such as Cys4 tag (tetracysteine; Cys-Cys-X-X-Cys-Cys) are l...
Single-fluorophore membrane transport activity sensors with dual-emission read-out.
We recently described a series of genetically encoded, single-fluorophore-based sensors, termed AmTrac and MepTrac, which monitor membrane transporter activity in vivo...
Aptamer-functionalized nanoporous gold film for high-performance direct electrochemical detection of bisphenol A in human serum.
In the present work, a highly sensitive and selective biosensor based on aptamer-functionalized nanoporous gold film (NPGF) was successfully developed for direct elect...
Analysis of Phthalate Esters in Mammalian Cell Culture Using a Microfluidic Channel Coupled with an Electrochemical Sensor.
An analytical tool to monitor trace phthalate was developed using a microfluidic channel device coupled with a novel electrochemical biosensor. At first, the electroch...
Real-time monitoring of mechanical changes during dynamic adhesion of erythrocytes to endothelial cells by QCM-D.
A quartz crystal microbalance with dissipation monitoring is used to measure changes in mechanical properties of diabetic red blood cells (RBCs) and normal RBCs. Moreo...
Determination of binding capacity and adsorption enthalpy between Human Glutamate Receptor (GluR1) peptide fragments and kynurenic acid by surface plasmon resonance experiments. Part 2: Interaction of GluR1270-300 with KYNA.
In the course of our previous work, the interactions of two peptide fragments (GluR1201-230 and GluR1231-259) of human glutamate receptor (GluR1201-300) polypeptide wi...
Paramagnetic relaxation based biosensor for selective dopamine detection.
We report a new NMR relaxation time-based method for sensitive and selective dopamine detection using paramagnetic nanoparticles. The Fe(3+) species in the nanoparticl...
Amplified solid-state electrochemiluminescence detection of cholesterol in near-infrared range based on CdTe quantum dots decorated multiwalled carbon nanotubes@reduced graphene oxide nanoribbons.
An amplified solid-state electrochemiluminescence (ECL) biosensor for detection of cholesterol in near-infrared (NIR) range was constructed based on CdTe quantum dots ...
Enzymatic Polymerization on DNA Modified Gold Nanowire for Label-Free Detection of Pathogen DNA.
This paper presents a label-free biosensor for the detection of single-stranded pathogen DNA through the target-enhanced gelation between gold nanowires (AuNW) and the...
Self-interconnecting Pt nanowire network electrode for electrochemical amperometric biosensor.
One-dimensional Pt nanostructures are of considerable interest for the development of highly stable and sensitive electrochemical sensors. This paper describes a self-...