Levodopa: From Biological Significance to Continuous Monitoring.
A continuous levodopa sensor can improve the quality of life for patients suffering with Parkinson's disease by enhancing levodopa titration and treatment effectivenes...
DNA aptamer-functionalized PDA nanoparticles: from colloidal chemistry to biosensor applications.
Polydopamine nanoparticles (PDA NPs) are widely utilized in the field of biomedical science for surface functionalization because of their unique characteristics, such...
Nano-Photonic Crystal D-Shaped Fiber Devices for Label-Free Biosensing at the Attomolar Limit of Detection.
Maintaining both high sensitivity and large figure of merit (FoM) is crucial in regard to the performance of optical devices, particularly when they are intended for u...
Modular Fabrication of Microfluidic Graphene FET for Nucleic Acids Biosensing.
Graphene field-effect transistors (GFETs) are widely used in biosensing due to their excellent properties in biomolecular signal amplification, exhibiting great potent...
Extremely Sensitive Genetically Encoded Temperature Indicator Enabling Measurement at the Organelle Level.
Intracellular temperature is a fundamental parameter in biochemical reactions. Genetically encoded fluorescent temperature indicators (GETIs) have been developed to vi...
Hexagonal Plasmonic Arrays for High-Throughput Multicolor Single-Molecule Studies.
Nanophotonic biosensors offer exceptional sensitivity in the presence of strong background signals by enhancing and confining light in subwavelength volumes. In the fi...
Sensitive fluorescence detection of miRNA-124 in cardiomyocytes under oxidative stress using a nucleic acid probe.
MicroRNAs (miRNAs) are small noncoding RNAs of 18-25 bases. miRNAs are also important new biomarkers that can be used for disease diagnosis in the future. Studies have...
Recent advances in the metamaterial and metasurface-based biosensor in the gigahertz, terahertz, and optical frequency domains.
Recently, metamaterials and metasurface have gained rapidly increasing attention from researchers due to their extraordinary optical and electrical properties. Metamat...
CRISPR/Cas12a-Based APE1 Enzyme Cleavage Assay for Drug Resistance Analysis of
Drug resistance analysis of Staphylococcus aureus is responsible for generating significant mortality and morbidity in numerous diseases. However, sensitive and accura...
Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology.
Formaldehyde is a key metabolite in natural and synthetic one-carbon metabolism. To facilitate the engineering of formaldehyde-producing enzymes, the development of se...
Enhancing electrochemical detection through machine learning-driven prediction for canine mammary tumor biomarker with green silver nanoparticles.
This study developed an innovative biosensor strategy for the sensitive and selective detection of canine mammary tumor biomarkers, cancer antigen 15-3 (CA 15-3) and m...
Electrochemical biosensors for the detection of protozoan parasite: a scoping review.
The development of rapid, accurate, and efficient detection methods for protozoan parasites can substantially control the outbreak of protozoan parasites infection, wh...
Ligify: Automated Genome Mining for Ligand-Inducible Transcription Factors.
Prokaryotic transcription factors can be repurposed into biosensors for the ligand-inducible control of gene expression, but the landscape of chemical ligands for whic...
Implementation of Glucose-6-Phosphate Dehydrogenase (G6PD) testing for Plasmodium vivax case management, a mixed method study from Cambodia.
Plasmodium vivax remains a challenge for malaria elimination since it forms dormant liver stages (hypnozoites) that can reactivate after initial infection. 8-aminoquin...
Nanohole array integrated metal insulator metal (MIM) based structure employing dual mode SPR sensor for detection of Hemoglobin (Hb) in blood.
Surface Plasmon Resonance (SPR) based optical biosensors are recently the most attractive sensing devices that can detect minor changes in refractive index. Multiple m...
CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function.
Given the mounting evidence implicating TDP-43 dysfunction in several neurodegenerative diseases, there is a pressing need to establish accessible tools to sense and q...
A high oxidase-like activity, bimetallic single-atom nanozyme FeCe/NC prepared by FeCe-ZIF-8 approach for sensing tannic acid in tea.
To improve the activity of single-atom nanozymes (SAzymes) for applications in food analysis, a new bimetal SAzyme FeCe/NC was developed. Its oxidase-like activity is ...
Early fetal sex determination using a fluorescent DNA nanosensing platform capable of simultaneous detection of
Early fetal sex determination is of crucial importance in the management of prenatal diagnosis of X-linked genetic abnormalities and congenital adrenal hyperplasia. Th...
Enhancing the performance of porous silicon biosensors: the interplay of nanostructure design and microfluidic integration.
This work presents the development and design of aptasensor employing porous silicon (PSi) Fabry‒Pérot thin films that are suitable for use as optical transducers for ...
Emerging Designs and Applications for Biomembrane Biosensors.
Nature has inspired the development of biomimetic membrane sensors in which the functionalities of biological molecules, such as proteins and lipids, are harnessed for...