Studying the electronic properties of SiO
This study investigates the electronic properties of a proposed composite structure consisting of SiO2, Pb3O4, Bi2O3, and graphene oxide (GO) for glutamic acid (Glu) b...
Optimised nanobody-based quenchbodies for enhanced protein detection.
Quenchbodies, antibodies labelled with fluorophores that increase in intensity upon antigen binding, offer great promise for biosensor development. Nanobody-based quen...
A plant-insertable multi-enzyme biosensor for the real-time monitoring of stomatal sucrose uptake.
Monitoring sucrose transport in plants is essential for understanding plant physiology and improving agricultural practices, yet effective sensors for continuous and r...
Recent Advances in the Development of Functional Nucleic Acid Biosensors Based on Aptamer-Rolling Circle Amplification.
Aptamers are synthetic nucleic acids or peptides that exhibit high specificity and affinity for target molecules such as small molecules, proteins, or cells. Due to th...
An Anti-BCMA Affibody Affinity Protein for Therapeutic and Diagnostic Use in Multiple Myeloma.
B Cell Maturation Antigen (BCMA) has gained considerable attention as a target in directed therapies for multiple myeloma (MM) treatment, via immunoglobulin-based bisp...
Detection of Cadherin 12 in Plasma and Peritoneal Fluid Among Women with Endometriosis Using Novel Surface Plasmon Resonance Imaging (SPRi) Method.
Background: Endometriosis is a common gynecological disease linked to significant diagnostic challenges. Cadherin 12 (CDH12), as a member of adhesion molecules, is sup...
Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation.
The "Pain Overlap Theory"1 proposes that the experience of social pain overlaps with and amplifies the experience of physical pain by sharing parts of the same underly...
Photoelectrochemical Biosensor Based on 1D In
In photoelectrochemical (PEC) biosensing, efficient electron-hole separation is crucial to obtain preferred photocurrent response and analytical performance; thus, con...
Long-term culture and morphological maturation of taste organoids enhance taste discrimination in a biomimetic biosensor.
Taste is a multifaceted sensory experience that involves various human senses related to food and is a key indicator of food quality. A biomimetic taste-based biosenso...
Design of the DETECT project: automated cardiac arrest detection and activation of the emergency medical chain integrated into a wristband.
INTRODUCTION: While survival rates for witnessed out-of-hospital cardiac arrest have improved, assistance for unwitnessed cases often arrives too late. Automated cardi...
CRISPR-Cas13a as a next-generation tool for rapid and precise plant RNA virus diagnostics.
Plant viruses are among the most serious threats to global agriculture, causing significant yield losses and jeopardizing food security. Identifying these viruses is c...
A critical review of conventional and emerging technologies for the detection of contaminants, allergens and adulterants in plant-based milk alternatives.
The increasing popularity of plant-based milk alternatives (PBMAs) necessitates effective safety and authentication measures to ensure food product integrity and maint...
Evolutionary Trajectories of Methionine Metabolism in Mycobacterium and Its Application to Engineer a Vitamin B12 Whole-Cell Ribosensor.
Vitamin B12 metabolism differs among members of the Mycobacterium genus. While non-tuberculous mycobacterial species are B12 producers, tuberculous mycobacteria lack e...
Modular and signal-responsive transcriptional regulation using CRISPRi-aided genetic switches in Escherichia coli.
BACKGROUND: Precise and dynamic transcriptional regulation is a cornerstone of synthetic biology, enabling the construction of robust genetic circuits and programmable...
Plasmonic optical fiber biosensors for ultra-low detection of respiratory syncytial virus via point-of-care tests.
Respiratory syncytial virus (RSV) is a major cause of bronchiolitis and pneumonia, particularly in children, the elderly, and immunocompromised individuals. Despite si...
Automated microfluidic electrochemical biosensor for the detection of immune-mediated thrombotic disorders.
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a new disorder that emerged in the wake of COVID-19 vaccination. It is a rare but life-threating condition...
Applications and development trend of biosensors in the detection and diagnosis of gastrointestinal tumors.
Gastrointestinal malignancies present a significant menace to the well-being of people across the globe. Consequently, the prompt and precise identification of such tu...
Circulating tumor cells: overcoming challenges of detecting a needle in a haystack.
Circulating tumor cells (CTCs) are cancer cells that are detached from the primary and metastatic tumor site and invade the bloodstream. Most importantly, CTCs are the...
Mitochondrial medicine: "from bench to bedside" 3PM-guided concept.
Mitochondria are the primary sites for aerobic respiration and play a vital role in maintaining physiologic function at the cellular and organismal levels. Physiologic...
Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor.
Heparan sulphate proteoglycans (HSPGs) are cell surface and extracellular matrix proteoglycan family members, playing a key role in diverse biological activities inclu...