Evaluating Cellular Drug Uptake with Fluorescent Sensor Proteins.
We are introducing a new approach to evaluate cellular uptake of drugs and drug candidates into living cells. The approach is based on converting the protein target of...
Anti-IL8/AuNPs-rGO/ITO as an Immunosensing Platform for Noninvasive Electrochemical Detection of Oral Cancer.
An efficient electrochemical transducer matrix for biosensing devices requires specific characteristics, such as fast electron transfer, stability, high surface area, ...
Transport Effects on Multiple-Component Reactions in Optical Biosensors.
Optical biosensors are often used to measure kinetic rate constants associated with chemical reactions. Such instruments operate in the surface-volume configuration, i...
CVD graphene as an electrochemical sensing platform for simultaneous detection of biomolecules.
The development of electrochemical biosensors for the simultaneous detection of ascorbic acid (AA), dopamine (DA), uric acid (UA), tryptophan (Trp), and nitrite ([Form...
Peptide nucleic acids: Advanced tools for biomedical applications.
Peptide Nucleic Acids (PNAs) are the DNA/RNA analogues in which sugar-phosphate backbone is replaced by N-2-aminoethylglycine repeating units. PNA contains neutral bac...
Microcantilever array instrument based on optical fiber and performance analysis.
We developed a microcantilever array biosensor instrument based on optical readout from a microcantilever array in fluid environment. The microcantilever signals were ...
Acriflavine-immobilized eggshell membrane as a new solid-state biosensor for Sudan I-IV detection based on fluorescence resonance energy transfer.
A novel solid-surface fluorescence biosensor for rapid detection of Sudan I-IV was proposed based on fluorescence resonance energy transfer (FRET). The biosensor was f...
Electroanalysis and laccase-based biosensor on the determination of phenolic content and antioxidant power of honey samples.
Honey is a functional food widely consumed. Thus, the evaluation of honey samples to determine its phenolic content and antioxidant capacity (AOC) is relevant to deter...
Fundamental Design Principles for Transcription-Factor-Based Metabolite Biosensors.
Metabolite biosensors are central to current efforts toward precision engineering of metabolism. Although most research has focused on building new biosensors, their t...
Sensitive detection of microRNAs based on the conversion of colorimetric assay into electrochemical analysis with duplex-specific nuclease-assisted signal amplification.
miRNAs have emerged as new biomarkers for the detection of a wide variety of cancers. By employing duplex-specific nuclease for signal amplification and gold nanoparti...
Electrochemical detection of interaction between capsaicin and nucleic acids in comparison to agarose gel electrophoresis.
In this study, the biomolecular interaction occurred between nucleic acids and Capsaicin (CPS), the active compound in chilli peppers, which has been reported to have ...
TiO
This work designed a nanocomposite to enhance the photoelectrochemical (PEC) efficiency by depositing BiVO4 nanoparticles on TiO2 nanospheres with a solvothermal metho...
CeO₂ Nanorods Embedded in Ni(OH)₂ Matrix for the Non-Enzymatic Detection of Glucose.
The electrode based on cerium oxide (CeO₂) nanorods embedded in nickel hydroxide (Ni(OH)₂) matrix were prepared and used for detecting glucose non-enzymatically. The m...
Proline dehydrogenase-entrapped mesoporous magnetic silica nanomaterial for electrochemical biosensing of L-proline in biological fluids.
In this work, physical adsorption was used for immobilization of proline dehydrogenase onto a magnetic mesoporous silica nanomaterial. The immobilization and electroca...
Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays.
Spreading depolarization (SD) is a slow propagating wave of strong depolarization of neural cells, implicated in several neuropathological conditions. The breakdown of...
Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy.
While increased mitochondrial reactive oxygen species have been commonly implicated in a variety of disease states, their in vivo role in the pathogenesis of diabetic ...
Applicability of Metal Nanoparticles in the Detection and Monitoring of Hepatitis B Virus Infection.
Chronic infection with the hepatitis B virus (HBV) can lead to liver failure and can cause liver cirrhosis and hepatocellular carcinoma (HCC). Reliable means for detec...
Integrated Biosensor Assay for Rapid Uropathogen Identification and Phenotypic Antimicrobial Susceptibility Testing.
BACKGROUND: Standard diagnosis of urinary tract infection (UTI) via urine culture for pathogen identification (ID) and antimicrobial susceptibility testing (AST) takes...
Multimode smartphone biosensing: the transmission, reflection, and intensity spectral (TRI)-analyzer.
We demonstrate a smartphone-integrated handheld detection instrument capable of utilizing the internal rear-facing camera as a high-resolution spectrometer for measuri...
Binary Nanoparticle Graphene Hybrid Structure-Based Highly Sensitive Biosensing Platform for Norovirus-Like Particle Detection.
Nanoparticle (NP)-decorated carbon nanotubes or graphenes (GRPs) have attracted attention because of their synergic properties such as enhanced electrical conductivity...