Giant Catalytic DNA Particles for Simple and Intuitive Detection of Pb(2.).
DNAzymes have been extensively studied as biosensors because of their unique functionality of cleaving substrate in the presence of metal ion cofactors. However, there...
Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications.
Surveillance using biomarkers is critical for the early detection, rapid intervention, and reduction in the incidence of diseases. In this study, we describe the prepa...
Specific Magnetic Isolation of E6 HPV16 Modified Magnetizable Particles Coupled with PCR and Electrochemical Detection.
The majority of carcinomas that were developed due to the infection with human papillomavirus (HPV) are caused by high-risk HPV types, HPV16 and HPV18. These HPV types...
Soluble Amyloid-β42 Stimulates Glutamate Release through Activation of the α7 Nicotinic Acetylcholine Receptor.
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory loss and hippocampal atrophy. Soluble amyloid-β (Aβ)42 and pl...
Methods for the Specific Detection and Quantitation of Amyloid-β Oligomers in Cerebrospinal Fluid.
Protein misfolding and aggregation are fundamental features of the majority of neurodegenerative diseases, like Alzheimer's disease (AD), Parkinson's disease, frontote...
Cleavage of Hyaluronan and CD44 Adhesion Molecule Regulate Astrocyte Morphology via Rac1 Signalling.
Communication of cells with their extracellular environment is crucial to fulfill their function in physiological and pathophysiological conditions. The literature dat...
Cyanidin inhibits quorum signalling pathway of a food borne opportunistic pathogen.
Quorum sensing (QS) is the process of population dependent cell to cell communication used by bacteria to regulate their phenotypic characteristics. Key virulence fact...
Electrochromic sensing platform based on steric hindrance effects for CEA detection.
In this work, an electrochromic sensing platform with prussian blue (PB) as the indicator was proposed for signaling carcinoembryonic antigen (CEA) using the bipolar e...
Engineered bacteria detect spatial profiles in glucose concentration within solid tumor cell masses.
Tumor heterogeneity makes cancer difficult to treat. Many small molecule cancer drugs target rapidly dividing cells on the periphery of tumors but have difficulty in p...
The catalytic activity of Ag2S-montmorillonites as peroxidase mimetic toward colorimetric detection of H2O2.
Nanocomposites based on silver sulfide (Ag2S) and Ca-montmorillonite (Ca(2+)-MMT) were synthesized by a simple hydrothermal method. The nanocomposites were characteriz...
A biolayer interferometry-based assay for rapid and highly sensitive detection of biowarfare agents.
Biolayer interferometry (BLI) is an optical technique that uses fiber-optic biosensors for label-free real-time monitoring of protein-protein interactions. In this stu...
Embroidered electrochemical sensors for biomolecular detection.
Electrochemical sensors are powerful analytical tools which possess the capacity for rapid detection of biomarkers in clinical specimens. While most electrochemical se...
An electrochemical DNA biosensor based on Oracet Blue as a label for detection of Helicobacter pylori.
An innovative method of a DNA electrochemical biosensor based on Oracet Blue (OB) as an electroactive label and gold electrode (AuE) for detection of Helicobacter pylo...
In vitro selection and amplification protocols for isolation of aptameric sensors for small molecules.
We recently optimized a procedure that directly yields aptameric sensors for small molecules in so-called structure-switching format. The protocol has a high success r...
Coupling non invasive and fast sampling of proteins from work of art surfaces to surface plasmon resonance biosensing: Differential and simultaneous detection of egg components for cultural heritage diagnosis and conservation.
Despite the wide application of surface plasmon resonance (SPR) to a broad area of interests, from environment to food analysis, from drug discovery to diagnostics, it...
Aptamers, antibody scFv, and antibody Fab' fragments: An overview and comparison of three of the most versatile biosensor biorecognition elements.
The choice of biosensing elements is crucial for the development of the optimal biosensor. Three of the most versatile biosensing elements are antibody single-chain Fv...
Selection and characterization of DNA aptamers for the development of light-up biosensor to detect Cd(II).
In order to develop a facile, cost-effective and quick-testing light-up biosensor with excellent specificity for cadmium ions (Cd(II)) detection, a modified selection ...
Electrochemical functionalization of polypyrrole through amine oxidation of poly(amidoamine) dendrimers: Application to DNA biosensor.
Electrochemical patterning method has been developed to fabricate composite based on polypyrrole (PPy) film and poly(amidoamine) dendrimers of fourth generation (PAMAM...
Amperometric biosensor based on Laccase immobilized onto a screen-printed electrode by Matrix Assisted Pulsed Laser Evaporation.
A Laccase-based biosensor for the determination of phenolic compounds was developed by using Matrix Assisted Pulsed Laser Evaporation as an innovative enzyme immobiliz...
Electrochemical DNA biosensor based on poly(2,6-pyridinedicarboxylic acid) modified glassy carbon electrode for the determination of anticancer drug gemcitabine.
In this study, a simple methodology was used to develop a new electrochemical DNA biosensor based on poly(2,6-pyridinedicarboxylic acid) (P(PDCA)) modified glassy carb...