Bacteriorhodopsin-Based pH Sensor for Cell Culture Condition Regulation.
In cell culture research and biotechnology, precise pH monitoring is crucial for maintaining cellular health and ensuring reliable experimental outcomes. Traditional p...
Constructing Photoactive Au NP/MXene-BiOCl Moiré Superlattice Nanosheets for Photoelectrochemical Detection of Protein Kinase Activity.
A novel photoelectrochemical (PEC) biosensor was proposed by preparing Au NP/MXene-BiOCl Moiré superlattice nanosheets as the probes. Upon irradiation with visible lig...
pH-Responsive Triplex DNA Nanoswitches: Surface Plasmon Resonance Platform for Bladder Cancer-Associated microRNAs.
Bladder cancer (BC) has a high recurrence rate, necessitating frequent monitoring. We herein present an innovative method for detecting BC-related miR-183 and miR-155 ...
Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins.
Genetically encoded lipid biosensors uniquely provide real time, spatially resolved kinetic data for lipid dynamics in living cells. Despite clear strengths, these too...
A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine.
This study introduces a 2-D Photonic Crystal (PhC) biosensor designed, simulated, and evaluated for detecting glucose concentrations in urine by utilizing refractive i...
Customization of Ethylene Glycol (EG)-Induced BmoR-Based Biosensor for the Directed Evolution of PET Degrading Enzymes.
The immense volume of plastic waste poses continuous threats to the ecosystem and human health. Despite substantial efforts to enhance the catalytic activity, robustne...
Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring.
The epithelial-mesenchymal transition (EMT) is a critical process for cancer to metastasize by promoting invasiveness and dissemination of cancer cells in the body. Un...
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Dengue fever, a mosquito-borne viral infection, poses a significant global health challenge, particularly in tropical and subtropical regions. The absence of non-effec...
Nanozyme-based aptasensors for the detection of tumor biomarkers.
A nanozyme-based aptasensor combines the unique properties of nanozymes with the specificity of aptamers for the detection of various biomolecules. Nanozymes are nanom...
Alternative Approach to Sequence-Specific Recognition of DNA: Cooperative Stacking of Dication Dimers─Sensitivity to Compound Curvature, Aromatic Structure, and DNA Sequence.
With the growing number and diversity of known genome sequences, there is an increasing opportunity to regulate gene expression through synthetic, cell-permeable small...
A split ribozyme system for in vivo plant RNA imaging and genetic engineering.
RNA plays a central role in plants, governing various cellular and physiological processes. Monitoring its dynamic abundance provides a discerning understanding of mol...
Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network.
The increasing consumption of fossil fuels is contributing to global resource depletion and environmental pollution. Branched-chain higher alcohols, such as isopentano...
Comparative Kinetics of Supported Lipid Bilayer Formation on Silica Coated Vertically Oriented Highly Curved Nanowires and Planar Silica Surfaces.
Supported lipid bilayers (SLBs), formed via lipid vesicle adsorption on highly curved silica surfaces, are widely used in biosensor applications and as models for curv...
Ga@MXene-based flexible wearable biosensor for glucose monitoring in sweat.
Most wearable biosensors struggle to balance flexibility and conductivity in their sensing interfaces. In this study, we propose a wearable sensor featuring a highly s...
Colorimetric CRISPR Biosensor: A Case Study with Salmonella Typhi.
There is a critical need to implement a sensitive and specific point-of-care (POC) biosensor that addresses the instrument limitations and manufacturing challenges fac...
Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m
BACKGROUND: D-2-hydroxyglutarate (D-2HG), an oncometabolite derived from the tricarboxylic acid cycle. Previous studies have reported the diverse effects of D-2HG in p...
A qualitative exploration of the experiences of transdermal alcohol sensor devices amongst alcohol service practitioners (South London, UK).
BACKGROUND: A qualitative exploration into the views of alcohol service staff on transdermal alcohol sensors (TAS) within three alcohol services in South London, UK. T...
Biomimetic Hydrogels - Tools for Regenerative Medicine, Oncology, and Understanding Medical Gas Plasma Therapy.
Biomimetic hydrogels enable biochemical, cell biology, and tissue-like studies in the third dimension. Smart hydrogels are also frequently used in tissue engineering a...
Recent developments in waterborne pathogen detection technologies.
Waterborne pathogens find their way into water bodies through contamination of fecal discharge, stormwater run-offs, agriculture and industrial activities, and poor wa...
Current biosensing strategies based on in vitro T7 RNA polymerase reaction.
Recently, a unique behavior of T7 RNA polymerase has expanded its functionality as a biosensing platform. Various biosensors utilizing T7 RNA polymerase, combined with...