ATP metabolism in skeletal muscle arterioles.
The purpose of this study was to investigate the metabolism of Adenosine triphosphate (ATP) in skeletal muscle resistance arterioles and to determine whether this meta...
Synthetic RNA switches for yeast metabolic engineering: screening recombinant enzyme libraries.
Directed evolution is a powerful technique for increasing the activity of poorly active enzymes, for example when an enzyme is engineered to accept a new substrate or ...
Scalable production of highly sensitive nanosensors based on graphene functionalized with a designed G protein-coupled receptor.
We have developed a novel, all-electronic biosensor for opioids that consists of an engineered μ-opioid receptor protein, with high binding affinity for opioids, chemi...
Sequential pH-dependent adsorption of ionic amphiphilic diblock copolymer micelles and choline oxidase onto conductive substrates: toward the design of biosensors.
This work examines the fabrication regime and the properties of polymer-enzyme thin-films adsorbed onto conductive substrates (graphite or gold). The films are formed ...
A protein-based electrochemical biosensor for detection of tau protein, a neurodegenerative disease biomarker.
A protein-based electrochemical biosensor was developed for detection of tau protein aimed towards electrochemically sensing misfolding proteins. The electrochemical a...
Facile synthesis of Au-SnO2 hybrid nanospheres with enhanced photoelectrochemical biosensing performance.
Au-SnO2 hybrid nanospheres (HNSs) were synthesized by a facile, one-step method, which was achieved via a redox reaction between the reductive stannous (II) ions and o...
Potential of cross-priming amplification and DNA-based lateral-flow strip biosensor for rapid on-site GMO screening.
The requirement to monitor the presence of genetically modified organisms (GMO) in a variety of marked products has generated an increasing demand for reliable, rapid,...
Isolation of the autoinducer-quenching strain that inhibits LasR in Pseudomonas aeruginosa.
Quorum sensing (QS) has been recognized as a general phenomenon in microorganisms and plays an important role in many pathogenic bacteria. In this report, we used the ...
Aptamer-based biosensors for biomedical diagnostics.
Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most aptamers are obtained through a combinatorial biology technique called SELEX...
The transformation of common office supplies into a low-cost optical biosensing platform.
By reassembling common office supplies, an optical biosensing system was developed. A laser pointer and the solar cell from a calculator were utilized in the developed...
Universal biosensor for detection of influenza virus.
Influenza is a contagious disease caught by humans caused by viruses belonging to the family Orthomyxoviridae. Each year, the influenza virus infects millions of peopl...
Detection of the antiepileptic drug phenytoin using a single free-standing piezoresistive microcantilever for therapeutic drug monitoring.
Phenytoin, one of the most widely used antiepileptic drugs, suppresses the abnormal brain activity often seen in seizures. In this study, we report the electrical dete...
A novel hydrogen peroxide biosensor based on hemoglobin-collagen-CNTs composite nanofibers.
In this paper, carbon nanotubes (CNTs) were successfully incorporated in the composite composed of hemoglobin (Hb) and collagen using co-electrospinning technology. Th...
A pyranose dehydrogenase-based biosensor for kinetic analysis of enzymatic hydrolysis of cellulose by cellulases.
A novel electrochemical enzyme biosensor was developed for real-time detection of cellulase activity when acting on their natural insoluble substrate, cellulose. The e...
An acetylcholinesterase biosensor based on graphene-gold nanocomposite and calcined layered double hydroxide.
In this study, a novel acetylcholinesterase-based biosensor was fabricated. Acetylcholinesterase (AChE) was immobilized onto a glassy carbon electrode (GCE) with the a...
Multicolor fluorescent biosensor for multiplexed detection of DNA.
Development of efficient methods for highly sensitive and rapid screening of specific oligonucleotide sequences is essential to the early diagnosis of serious diseases...
A novel integrated biosensor based on co-immobilizing the mediator and microorganism for water biotoxicity assay.
A novel integrated biosensor for biotoxicity assay has been developed by co-immobilizing microorganisms and mediators within a novel redox hydrogel. The proposed redox...
Bioplasmonic calligraphy for multiplexed label-free biodetection.
Printable multi-marker biochips that enable simultaneous quantitative detection of multiple target biomarkers in point-of-care and resource-limited settings are a holy...
Flower-like ZnO nanostructure based electrochemical DNA biosensor for bacterial meningitis detection.
Zinc oxide (ZnO) nanostructures possessing flower-like morphology have been synthesised onto platinized silicon substrate by simple and economical hydrothermal method....