Biosensor-based enzyme engineering approach applied to psicose biosynthesis.
Bioproduction of chemical compounds is of great interest for modern industries, as it reduces their production costs and ecological impact. With the use of synthetic b...
Spiropyran as a potential molecular diagnostic tool for double-stranded RNA detection.
BACKGROUND: Long double-stranded RNAs (dsRNAs) are duplex RNAs that can induce immune response when present in mammalian cells. These RNAs are historically associated ...
Innovative engineering and sensing strategies for aptamer-based small-molecule detection.
Aptamers are nucleic acid-based affinity reagents that have gained widespread attention as biorecognition elements for the detection of targets such as ions, small mol...
Direct measurement of deubiquitinating enzyme activity in intact cells using a protease-resistant, cell-permeable, peptide-based reporter.
Deubiquitinating enzymes (DUBs) regulate the removal of the polyubiquitin chain from proteins targeted for degradation. Current approaches to quantify DUB activity are...
Developing new SrI
In the context of personalized medicine, there is a growing interest in materials bearing at the same time diagnostic and therapy functions. This article reports a che...
Frontiers in Electrochemical Sensors for Neurotransmitter Detection: Towards Measuring Neurotransmitters as Chemical Diagnostics for Brain Disorders.
It is extremely challenging to chemically diagnose disorders of the brain. There is hence great interest in designing and optimizing tools for direct detection of chem...
A biosensor for measuring NAD
The cellular level of nicotinamide adenine dinucleotide (NAD+), through its different functions, affects cellular metabolism and signalling1-3. A decrease in the NAD+ ...
Al
Whispering gallery mode resonator lasers hold the promise of an ultralow intrinsic limit of detection. However, the widespread use of these devices for biosensing appl...
An electrochemical biosensor for prostate cancer biomarker detection using graphene oxide-gold nanostructures.
In this paper, a most sensitive electrochemical biosensor for detection of prostate-specific antigen (PSA) was designed. To reach the goal, a sandwich type electrode c...
Commentary regarding: "Activity determination of FAD-dependent glucose dehydrogenase immobilized in PEDOT: PSS-PVA composite films for biosensor applications".
In the light of continuous improvement and optimization, recent experiments that the authors conducted give new insights into the applied evaluation method of Riegel e...
Monitoring bioactive and total antibody concentrations for continuous process control by surface plasmon resonance spectroscopy.
Monoclonal antibodies have become an increasingly important part of fundamental research and medical applications. To meet the high market demand for monoclonal antibo...
What directions of improvements in electrode designs should we expect in the next 5-10 years?
Glucose biosensor based on open-source wireless microfluidic potentiostat.
Wireless potentiostats capable of cyclic voltammetry and amperometry that connect to the Internet are emerging as key attributes of future point-of-care devices. This ...
A highly sensitive label-free electrochemical immunosensor based on an aligned GaN nanowires array/polydopamine heterointerface modified with Au nanoparticles.
Aligned GaN nanowire arrays show great potential not only in optoelectronic devices, but also in sensitive biosensor applications, owing to their excellent chemical st...
A novel ratiometric SERS biosensor with one Raman probe for ultrasensitive microRNA detection based on DNA hydrogel amplification.
In this work, a novel ratiometric SERS biosensor with only one Raman probe was fabricated in combination with the DNA hydrogel-captured glucose oxidase (GOx) amplifica...
Silver nanoparticle@DNA tetrahedron-based colorimetric detection of HIV-related DNA with cascade strand displacement amplification.
DNA tetrahedron-modified silver nanoparticles (AgNPs) were achieved via amino-silver chemistry for the first time and were applied as a colorimetric biosensor for dete...
A universal photoelectrochemical biosensor for dual microRNA detection based on two CdTe nanocomposites.
Various diseases are closely related to simultaneous changes of multiple miRNAs expression levels. It's of great significance to develop photoelectrochemical (PEC) bio...
Understanding how charge and hydrophobicity influence globular protein adsorption to alkanethiol and material surfaces.
Every biosensor, bioengineered scaffold or biomedical implant depends crucially on an ability to control protein adsorption at the material surface. Yet the adsorption...
Bio-modified carbon paste electrode for the detection of Pb(II) ions in wastewater.
Heavy metal pollution in water is a serious environmental concern. Lead is one of the highly toxic heavy metals, and its toxicity is due to its non-degradation charact...
Polycaprolactone-Based, Porous CaCO
Surface-enhanced Raman scattering (SERS) is a high-performance technique allowing detection of extremely low concentrations of analytes. For such applications, fibrous...