Nanobiosensors for procalcitonin (PCT) analysis.
BACKGROUND: Procalcitonin (PCT) is a critical biomarker that is released in response to bacterial infections and can be used to differentiate the pathogenesis of the i...
Sensor system for analysis of biofilm sensitivity to ampicillin.
The resistance of biofilms to antibiotics is a key factor that makes bacterial infections unsusceptible to antimicrobial therapy. The results of classical tests of cel...
Study of the reusability and stability of nylon nanofibres as an antibody immobilisation surface.
In the case of a biological threat, early, rapid, and specific detection is critical. In addition, ease of handling, use in the field, and low-cost production are impo...
New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of
A fast and sensitive aptasensor was developed using nanoplates with peroxidase activity as a novel approach. E. coli detection is described using a silver/platinum nan...
Transmembrane pH gradient imaging in rodent glioma models.
A unique feature of the tumor microenvironment is extracellular acidosis in relation to intracellular milieu. Metabolic reprogramming in tumors results in overproducti...
Evaluation of restriction and Cas endonuclease kinetics using matrix-insensitive magnetic biosensors.
The enzymatic actions of endonucleases in vivo can be altered due to bound substrates and differences in local environments, including enzyme concentration, pH, salini...
Validation of a plasmonic-based serology biosensor for veterinary diagnosis of COVID-19 in domestic animals.
The coronavirus disease 2019 (COVID-19) pandemic recently demonstrated the devastating impact on public health, economy, and social development of zoonotic infectious ...
Giving the cells what they need when they need it: Biosensor-based feeding control.
"Giving the cells exactly what they need, when they need it" is the core idea behind the proposed bioprocess control strategy: operating bioprocess based on the physio...
Miniaturization of CRISPR/Cas12-Based DNA Sensor Array by Non-Contact Printing.
DNA microarrays have been applied for comprehensive genotyping, but remain a drawback in complicated operations. As a solution, we previously reported the solid-phase ...
ACEK Biosensor for the Minute-Scale Quantification of Breast Cancer ctDNA.
Circulating tumor DNA (ctDNA) appears as a valuable liquid biopsy biomarker in the early diagnosis, treatment, and prognosis of cancer. Here, a biosensing method deriv...
From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics.
In the constantly evolving field of medical diagnostics, triboelectric nanogenerators (TENGs) stand out as a groundbreaking innovation for simultaneously harnessing me...
Recent Trends in Chemical Sensors for Detecting Toxic Materials.
Industrial development has led to the widespread production of toxic materials, including carcinogenic, mutagenic, and toxic chemicals. Even with strict management and...
Antibacterial and Anti-Quorum Sensing Properties of Silver Nanoparticles Phytosynthesized Using
The rise in antibiotic resistance (AR) poses an imminent threat to human health. Nanotechnology, together with mechanisms such as quorum sensing (QS), which relies on ...
New Advances in Rapid Pretreatment for Small Dense LDL Cholesterol Measurement Using Shear Horizontal Surface Acoustic Wave (SH-SAW) Technology.
Atherosclerosis is an inflammatory disease of the arteries associated with alterations in lipid and other metabolism and is a major cause of cardiovascular disease (CV...
Challenges for Field-Effect-Transistor-Based Graphene Biosensors.
Owing to its outstanding physical properties, graphene has attracted attention as a promising biosensor material. Field-effect-transistor (FET)-based biosensors are pa...
Ultrahigh-throughput screening-assisted in vivo directed evolution for enzyme engineering.
BACKGROUND: Classical directed evolution is a powerful approach for engineering biomolecules with improved or novel functions. However, it traditionally relies on labo...
Ultrasensitive and Rapid Detection of Procalcitonin via Waveguide-Enhanced Nanogold-Linked Immunosorbent Assay for Early Sepsis Diagnosis.
Sepsis, a life-threatening inflammatory response, demands economical, accurate, and rapid detection of biomarkers during the critical "golden hour" to reduce the patie...
10.1021/acschemneuro.3c00725
The recent development of genetically encoded fluorescent neurotransmitter biosensors has opened the door to recording serotonin (5-hydroxytryptamine, 5-HT) signaling ...
Pain-Free Alpha-Synuclein Detection by Low-Cost Hierarchical Nanowire Based Electrode.
Analytical methods for the early detection of the neurodegenerative biomarker for Parkinson's disease (PD), α-synuclein, are time-consuming and invasive, and require s...
Advanced Nanomaterial-Based Biosensors for N-Terminal Pro-Brain Natriuretic Peptide Biomarker Detection: Progress and Future Challenges in Cardiovascular Disease Diagnostics.
Cardiovascular diseases (CVDs) represent a significant challenge in global health, demanding advancements in diagnostic modalities. This review delineates the progress...