Electrochemical Profiling of vWFA2 for Systemic Inflammatory State Detection.
This research aims to develop a portable biosensor device for quickly detecting vWFA2, a biomarker for inflammatory conditions. This sensor could dramatically change d...
One-pot MCDA-CRISPR-Cas-based detection platform for point-of-care testing of severe acute respiratory syndrome coronavirus 2.
Compared to quantitative real-time PCR (q-PCR), CRISPR-Cas-mediated technology is more suitable for point-of-care testing (POCT) and has potential for wider applicatio...
Buffering of nuclear membrane tension and mechanotransduction by the endoplasmic reticulum revealed by quantitative ALPIN imaging.
Nuclear deformation by osmotic shock or necrosis activates the cytosolic phospholipase A2 (cPla2) nuclear shape sensing pathway, a key regulator of tissue inflammation...
An NIR-driven biosensor based on the metal-enhanced fluorescence effect and a signal amplification strategy for miRNA detection.
Research has shown that the expression level of microRNA-155 (miRNA-155) is positively correlated with clinical stage and depth of invasion in patients with cervical c...
An electrochemical biosensor for the detection of tuberculosis specific DNA with CRISPR-Cas12a and redox-probe modified oligonucleotide.
BACKGROUND: The development of a robust and accurate point-of-care platform for the detection of tuberculosis (TB) biomarkers is important for disease control. In the ...
Single-Walled Carbon Nanotubes as Optical Transducers for Nanobiosensors In Vivo.
Semiconducting single-walled carbon nanotubes (SWCNTs) may serve as signal transducers for nanobiosensors. Recent studies have developed innovative methods of engineer...
Determination of Lactoferrin Using High-Frequency Piezoelectric Quartz Aptamer Biosensor Based on Molecular Bond Rupture.
In this study, an aptamer biosensor for detecting lactoferrin (LF) was developed using piezoelectric quartz-induced bond rupture sensing technology. The thiol-modified...
Recent Advances in DNA Origami-Enabled Optical Biosensors for Multi-Scenario Application.
Over the past few years, significant progress has been made in DNA origami technology due to the unrivaled self-assembly properties of DNA molecules. As a highly progr...
Innovative Carbonaceous Materials and Metal/Metal Oxide Nanoparticles for Electrochemical Biosensor Applications.
Electrochemical biosensors have emerged as predominant devices for sensitive, rapid, and specific sensing of biomolecules, with significant applications in clinical di...
Bright Quantum-Grade Fluorescent Nanodiamonds.
Optically accessible spin-active nanomaterials are promising as quantum nanosensors for probing biological samples. However, achieving bioimaging-level brightness and ...
Biofilm formation by
The bacterial pathogen Staphylococcus aureus forms multicellular communities known as biofilms in which cells are held together by an extracellular matrix principally ...
Synthesis and Characterization of α,ω-End Orthogonally Functionalizable Glycopolymers from Native Glycans.
Glycopolymers have been employed as biomimetic glycoconjugates in both biological and biomedical research and applications. Among them, chain-end functionalized glycop...
Biodetection Strategies for Selective Identification of Candidiasis.
Fungi are among the predominant pathogens seen in a greater proportion of infections acquired in healthcare settings. A common fungus that causes infections in medical...
Synergism Between α-Terpineol and Terpinen-4-ol Potentiates Antivirulence Response Against
UNLABELLED: Antivirulence strategies have emerged as next-generation therapies that are now becoming refractory to the use of traditional antimicrobial approaches. Con...
REAL-TIME RECURSIVE ESTIMATION OF, AND UNCERTAINTY QUANTIFICATION FOR, BREATH ALCOHOL CONCENTRATION VIA LQ TRACKING CONTROL-BASED INVERSE FILTERING OF TRANSDERMAL ALCOHOL BIOSENSOR SIGNALS.
The utility of newly developed wearable biosensors for passively, non-invasively, and continuously measuring transdermal alcohol levels in the body in real time has be...
Two Novel Red-FRET ERK Biosensors in the 670-720nm Range.
Cell fate decisions are regulated by intricate signaling networks, with Extracellular signal-Regulated Kinase (ERK) being a central regulator. However, ERK is rarely t...
Chronic wound management: a liquid diode-based smart bandage with ultrasensitive pH sensing ability.
Chronic wounds, which require prolonged healing periods, pose significant impacts on individuals with diabetes, vascular diseases, and high blood pressure. Simultaneou...
A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor.
The Frizzled family (FZD1-10) of G protein-coupled receptors regulates WNT signaling mediating proliferative input. Dysregulation of FZD7 and exaggerated WNT/β-catenin...
pH-Dependent Conformational Plasticity of Monoclonal Antibodies at the SiO
Investigating the molecular conformations of monoclonal antibodies (mAbs) adsorbed at the solid/liquid interface is crucial for understanding mAb solution stability an...
Generating Real-World Evidence From the Excellence Network in Rheumatology.
PURPOSE: The Excellence Network in RheumatoloGY (ENRGY) was founded in 2021 and encompasses data from more than 700 private practice rheumatology providers throughout ...