共 25874 条结果
PLoS biology
2025
Wetherall B, Bulmer D, Sarginson A, Thomas C 等 5 人
During meiosis I in oocytes, anaphase is triggered by deactivation of cyclin B1-CDK1 and activation of separase. Active separase plays an essential role in cleaving co...
Frontiers in medicine
2025
Cao H, Oghenemaro EF, Latypova A, Abosaoda MK 等 6 人
Modern healthcare depends fundamentally on clinical biochemistry for disease diagnosis and therapeutic guidance. The discipline encounters operational constraints, inc...
Nature communications
2025
Huang R, Kravchik V, Zaatry R, Habib M 等 6 人
Synthetic multicellular systems have great potential for performing complex tasks, including multi-signal detection and computation through cell-to-cell communication....
Frontiers in bioengineering and biotechnology
2025
Alyamni N, Abot JL, Zestos AG
Carbon microelectrodes (CMEs) have emerged as pivotal tools in the field of neurochemical sensing, enabling precise, real-time monitoring of neurotransmitters in both ...
Journal of fluorescence
2025
Ozdemir A, Algül Y, Tirgil NY
Tro ponin is a biomolecule found in the blood of humans that can be used as an indicator of cardiac damage and cardiovascular risk. In this study, a turn-on fluorescen...
Biotechnology letters
2025
Maeno M, Sakuraba H, Ohshima T, Suye SI 等 5 人
This study aimed to address the stability limitations of third-generation biosensors using enzymes from mesophilic organisms, by engineering a stable direct electron t...
Chemistry (Weinheim an der Bergstrasse, Germany)
2025
Potter NS, Sokołowski K, Sala RL, McCune JA 等 5 人
There is great demand for biosensors capable of long-term, non-invasive monitoring of low analyte concentrations in various biofluids for diagnostics, personalized hea...
Fundamental research
2025
Wei X, Ren C, Liu B, Peng Y 等 5 人
Terahertz metamaterial biosensors combine terahertz time-domain spectroscopy with metamaterial sensing to provide a sensitive detection platform for a variety of targe...
Scientific reports
2025
Alghoul I, Hussain T, Nazir S, Tit N
Early diagnosis of gastric cancer (GC) is crucially important to initiate a therapy plan aiming at rescue and cure. In this regard, the detection of volatile organic c...
Respiratory research
2025
Liu Z, Bai Z, Chen X, Chen Y 等 8 人
Pulmonary hypertension (PH) is a serious disease characterized by elevated pulmonary artery pressure, with its prevalence and incidence continuously increasing, posing...
PLoS biology
2025
Sloan DC, Liao Y, Ray F, Muntean BS
G proteins (Gα and Gβγ subtypes) drive adenylyl cyclase type 5 (AC5) synthesis of cAMP in striatal neurons, which is essential for motor coordination. KCTD5 directly i...
PLoS computational biology
2025
Teoh YC, Noor MS, Aghakhani S, Girton J 等 6 人
A generalizable computational platform, CTRL-V (Computational TRacking of Likely Variants), is introduced to design selective binding (dual bait) biosensor proteins. T...
Conservation physiology
2025
Peterson EA, Keur MC, Yeboah M, van de Grootevheen T 等 9 人
Intertidal bivalves survive longer without oxygen when aerially exposed during low tide than when submerged in hypoxic water. To understand this, we combined three bio...
Sensors (Basel, Switzerland)
2025
Kim T, Pak JJ
We demonstrate a flexible electrochemical biosensor for non-enzymatic glucose detection under different bending conditions. The novel flexible glucose sensor consists ...
Diagnostics (Basel, Switzerland)
2025
Mageswaran N, Zainal SH, Hassan NI, Abd Karim NH 等 5 人
Coronary artery disease (CAD) is one of the primary causes of morbidity and death worldwide. Premature CAD (pCAD) is the term used to describe the 3-10% of CAD occurre...
Journal of clinical medicine
2025
Reddy KD, Chawla S
Advances in wearable technology have revolutionized healthcare by enabling the continuous monitoring of patients and personalized healthcare delivery. In the field of ...
Scientific reports
2025
Nyamdavaa A, Kaladharan K, Ganbold EO, Jeong S 等 8 人
The integration of Artificial Intelligence (AI) techniques with medical kits has revolutionized disease diagnosis, enabling rapid and accurate identification of variou...
Mikrochimica acta
2025
Ozbey S, Keles G, Kurbanoglu S
The isolation of a single atomic layer of graphite, known as graphene, marked a fundamental moment that transformed the field of materials science. Graphene-based nano...
Microsystems & nanoengineering
2025
Białas K, Tay HM, Petchakup C, Salimian R 等 8 人
Since the onset of the HIV epidemic, assessing CD4+ T-cells has become a routine procedure for evaluating immune deficiency, with flow cytometry established as the gol...
PloS one
2025
Meserve K, Chapman CA, Xu M, Zhou H 等 24 人
Active tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) bacteria and is characterized by multiple phases of infection, leading to difficulty in diagnosi...