Mitochondrial biosensors.
Biosensors offer an innovative tool for measuring the dynamics of a wide range of metabolites in living organisms. Biosensors are genetically encoded, and thus can be ...
Dip biosensor based on localized surface plasmon resonance at the tip of an optical fiber.
A dip biosensor is realized by depositing metallic nanoparticles onto the tip of a cleaved optical fiber. Light coupled into the fiber interacts with the localized sur...
Nanostructuring of biosensing electrodes with nanodiamonds for antibody immobilization.
While chemical vapor deposition of diamond films is currently cost prohibitive for biosensor construction, in this paper, we show that sonication-assisted nanostructur...
Silicon nanomaterials platform for bioimaging, biosensing, and cancer therapy.
Silicon nanomaterials are an important class of nanomaterials with great potential for technologies including energy, catalysis, and biotechnology, because of their ma...
Effect of processing parameters for electrocatalytic properties of SnO(2) thin film matrix for uric acid biosensor.
RF sputtered tin oxide (SnO2) thin film matrix has been efficiently exploited for the detection of uric acid. The deposition parameters for SnO2 thin film have been op...
Matrix rigidity regulates spatiotemporal dynamics of Cdc42 activity and vacuole formation kinetics of endothelial colony forming cells.
Recent evidence has shown that endothelial colony forming cells (ECFCs) may serve as a cell therapy for improving blood vessel formation in subjects with vascular inju...
Dual amplified and ultrasensitive electrochemical detection of mutant DNA Biomarkers based on nuclease-assisted target recycling and rolling circle amplifications.
Based on nicking endonuclease (NEase)-assisted target recycling and rolling circle amplification (RCA) for in situ generation of numerous G-quadruplex/hemin complexes,...
Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program.
Cell death contributes to the maintenance of homeostasis, but mounting evidence has confirmed the involvement of programmed cell death in some diseases. The concept of...
DNAzyme self-assembled gold nanorods-based FRET or polarization assay for ultrasensitive and selective detection of copper(II) ion.
In the paper, we have constructed a very simple, sensitive and promising assay for fluorescence biosensor detection of Cu(2+) in aqueous solutions based on FRET betwee...
Diagnosis of Epstein-Barr virus infection in clinical serum samples by an SPR biosensor assay.
Label-free affinity biosensors offer a promising platform for the development of a new generation of medical diagnostic technologies. Nevertheless, when such sensors a...
A simple hydrogen peroxide biosensor based on a novel electro-magnetic poly(p-phenylenediamine)@Fe3O4 nanocomposite.
The novel biocompatible poly(p-phenylenediamine) (PpPDA)-Fe3O4 nanocomposite (PpPDA@Fe3O4) was synthesized via emulsion polymerization. The PpPDA@Fe3O4 nanocomposite w...
Fabrication and characterization of a chemically oxidized-nanostructured porous silicon based biosensor implementing orienting protein A.
Nanostructured porous silicon (PSi) elicits as a very attractive material for future biosensing systems due to its high surface area, biocompatibility and well-establi...
Adsorption of DNA oligonucleotides by titanium dioxide nanoparticles.
Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomole...
Sub-femtomolar DNA detection based on layered molybdenum disulfide/multi-walled carbon nanotube composites, Au nanoparticle and enzyme multiple signal amplification.
A novel 2-dimensional graphene analog molybdenum disulfide/multi-walled carbon nanotube (MoS2/MWCNT) was synthesized by a simple hydrothermal method to achieve excelle...
Intra-molecular G-quadruplex structure generated by DNA-templated click chemistry: "turn-on" fluorescent probe for copper ions.
A novel homogenous fluorescent sensor for signal-on detection of Cu(2+) has been developed based on intra-molecular G-quadruplex formed by DNA-templated click reaction...
In situ electrochemical synthesis of highly loaded zirconium nanoparticles decorated reduced graphene oxide for the selective determination of dopamine and paracetamol in presence of ascorbic acid.
Highly loaded zirconium oxide (ZrO2) nanoparticles were supported on graphene oxide (ERGO/ZrO2) via an in situ, simple and clean strategy on the basis of the electroch...
Electrochemical biosensing platform using hydrogel prepared from ferrocene modified amino acid as highly efficient immobilization matrix.
To increase the loading of glucose oxidase (GOx) and simplify glucose biosensor fabrication, hydrogel prepared from ferrocene (Fc) modified amino acid phenylalanine (P...
Ratiometric fluorescence probe for monitoring hydroxyl radical in live cells based on gold nanoclusters.
Determination of hydroxyl radical ((•)OH) with high sensitivity and accuracy in live cells is a challenge for evaluating the role that (•)OH plays in the physiological...
Genetically encoded red fluorescent copper(I) sensors for cellular copper(I) imaging.
Copper ranks among the most important metal ions in living organism, owing to its key catalytic effect in a range of biochemical processes. Dysregulation of in vivo co...
Monoclonal antibody binding-site diversity assessment with a cell-based clustering assay.
The diversity of a panel of antibodies that target a specific antigen can be established in various assay formats. In conventional epitope binning assays purified anti...