Rho GTPase isoforms in cell motility: Don't fret, we have FRET.
The Rho-family of p21 small GTPases are directly linked to the regulation of actin-based motile machinery and play a key role in the control of cell migration. Aside f...
Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging.
Optimising response to tyrosine kinase inhibitors in cancer remains an extensive field of research. Intravital imaging is an emerging tool, which can be used in drug d...
Uptake, transport, distribution and Bio-effects of SiO2 nanoparticles in Bt-transgenic cotton.
BACKGROUND: SiO2 nanoparticle is one of the most popular nanomaterial which has been used in various fields, such as wastewater treatment, environmental remediation, f...
Rapid and sensitive detection of foodborne pathogenic bacteria (Staphylococcus aureus) using an electrochemical DNA genomic biosensor and its application in fresh beef.
Rapid early detection of food contamination is the main key in food safety and quality control. Biosensors are emerging as a vibrant area of research, and the use of D...
Design, synthesis, and evaluation of a selective chemosensor for leucine-rich repeat kinase 2.
We describe the design, synthesis, and evaluation of a selective activity probe for leucine-rich repeat kinase 2 (LRRK2), a possible molecular target for the treatment...
Sensitive and selective analysis of a wide concentration range of IGFBP7 using a surface plasmon resonance biosensor.
A sensitive method for selectively detecting insulin-like growth factor-binding protein 7 (IGFBP7) over a wide range of concentrations based on the surface plasmon res...
Determination of binding capacity and adsorption enthalpy between Human Glutamate Receptor (GluR1) peptide fragments and kynurenic acid by surface plasmon resonance experiments.
The interaction between kynurenic acid (KYNA) and two peptide fragments (ca. 30 residues) of Human Glutamate Receptor 201-300 (GluR1) using surface plasmon resonance (...
Porous polyurea network showing aggregation induced white light emission, applications as biosensor and scaffold for drug delivery.
We have designed a urea functionalized novel nanoporous material, POP-PU, which showsaggregation induced white light emission in the presence of suitable polar solvent...
Design and evaluation of a highly sensitive nanostructure-based surface modification of glassy carbon electrode for electrochemical studies of hydroxychloroquine in the presence of acetaminophen.
N,N'-bis[(E)-(1-pyridyl) methylidene]-1,3-propanediamine (PMPDA) self-assembled monolayer (SAM) was covalently prepared on a glassy carbon electrode (GCE). The electro...
Microwave annealing effect for highly reliable biosensor: dual-gate ion-sensitive field-effect transistor using amorphous InGaZnO thin-film transistor.
We used a microwave annealing process to fabricate a highly reliable biosensor using amorphous-InGaZnO (a-IGZO) thin-film transistors (TFTs), which usually experience ...
Electrochemical biosensor based on glucose oxidase encapsulated within enzymatically synthesized poly(1,10-phenanthroline-5,6-dione).
This study is focused on the investigation of electrocatalytic effect of glucose oxidase (GOx) immobilized on the graphite rod (GR) electrode. The enzyme modified elec...
Rapid identification of bacterial biofilms and biofilm wound models using a multichannel nanosensor.
Identification of infectious bacteria responsible for biofilm-associated infections is challenging due to the complex and heterogeneous biofilm matrix. To address this...
Confocal FLIM of genetically encoded FRET sensors for quantitative Ca2+ imaging.
Fluorescence lifetime imaging (FLIM) is a powerful imaging mode that can be combined with confocal imaging. Changes in the fluorescence decay time of a donor in an int...
A High-Content Assay for Biosensor Validation and for Examining Stimuli that Affect Biosensor Activity.
Biosensors are valuable tools used to monitor many different protein behaviors in vivo. Demand for new biosensors is high, but their development and characterization c...
Early diagnosis of blast fungus, Magnaporthe oryzae, in rice plant by using an ultra-sensitive electrically magnetic-controllable electrochemical biosensor.
As one of the most destructive and widespread disease of rice, Magnaporthe oryzae (also called Magnaporthe grisea) has a significant negative impact on rice production...
A label-free and high sensitive aptamer biosensor based on hyperbranched polyester microspheres for thrombin detection.
In this paper, we have synthesized hyperbranched polyester microspheres with carboxylic acid functional groups (HBPE-CA) and developed a label-free electrochemical apt...
Sarcosine oxidase composite screen-printed electrode for sarcosine determination in biological samples.
As the prostate cancer (PCa) progresses, sarcosine levels increase both in tumor cells and urine samples, suggesting that this metabolite measurements can help in the ...
The Agouti mouse: a biosensor for environmental epigenomics studies investigating the developmental origins of health and disease.
Sensitive electrochemical biosensing of H2O2 based on cobalt nanoparticles synthesised in iron storage protein molecules, ferritin.
In this report, a highly sensitive electrochemical biosensor based on cobaltferritin immobilised on a self-assembled monolayer modified gold electrode for determination...
Scalable low-cost fabrication of disposable paper sensors for DNA detection.
Controlled integration of features that enhance the analytical performance of a sensor chip is a challenging task in the development of paper sensors. A critical issue...