Modular Input-Output Biosensor Design Using
Protein-based biosensors offer unique advantages over conventional analytical methods by enabling real-time detection of target analytes with minimal sample preparatio...
Frontiers in aptamer-based diagnostics and therapeutics for zoonotic diseases.
Zoonotic diseases have become a significant public health concern due to their capacity to cross species barriers and cause widespread outbreaks. Conventional diagnost...
A directional nanoantenna design based on a hybrid plasmonic waveguide: theoretical analysis for biosensing applications.
This paper presents a novel rectangular aperture nano-antenna (RANA) design based on a hybrid plasmonic waveguide (HPW) configuration. The performance of the HPW is ev...
A designed peptide disrupting viral protease cleavage restores cGAS-DNA phase separation and type I interferon responses.
Seneca Valley Virus (SVV) 3C protease is essential for viral polyprotein processing and virion assembly. Meanwhile, it has evolved to cleave and antagonize the multipl...
Biosensors as transformative tools for multiplex detection of respiratory viral pathogens.
Respiratory viral infections remain a major global health challenge, highlighting the need for rapid, sensitive, and accessible diagnostic approaches. Conventional dia...
Palladium Porphyrin-Modified Fibrin Hydrogel for Oxygen Sensing in Engineered Skin Tissue Applications.
Tissue engineering is transforming regenerative medicine by enabling the creation of functional tissue substitutes for in vitro research and therapeutic applications. ...
Fluorescent carbon dot-based biosensor for the rapid and sensitive detection of Escherichia coli DNA.
Rapid and accurate detection of pathogenic bacteria is critical for healthcare, food safety, and environmental monitoring. Here, we report a carbon dot-based fluoresce...
Bacterial Fluorescence-Based Biosensor for Detecting Propionate in Culture Media for Diagnostic Applications.
BACKGROUND: Engineering bacteria for disease diagnosis and treatment is an emerging area of medical research that involves assessing short-lived molecules in complex, ...
Detection of mitochondrial bioenergetics using a novel bimodal 3D microelectrode array (MEA)-based biosensor.
Developing new label-free paradigms for functional assays in biomedical research has the potential to catalyze efforts in drug discovery and improve the understanding ...
A High-resolution metal-insulator-metal plasmonic biosensor with concentric ring resonators for carcinoembryonic antigen detection.
High-resolution optical sensors are vital for detecting subtle refractive index variations associated with biomolecular interactions, such as changes in carcinoembryon...
Longitudinal tracking of dyadic body temperature synchrony in social pairs across species.
Social behavior shapes efficient vocal communication and broadly impacts our mental health. While social interactions have been suggested to synchronize daily rhythmic...
Preparation, Interaction Mechanism and Application of Functional Ionic Liquid-Mediated Protein Imprinting Technique.
Protein recognition underpins advances in drug discovery, immunoassays, clinical diagnostics and biosensing. As a biomimetic alternative to natural receptors, molecula...
Affinity Peptide-Based Circularly Permuted Fluorescent Protein Biosensors Loaded in a Microfluidic System for Systemic Lupus Erythematosus Diagnosis.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, with anti-double-stranded DNA (anti-dsDNA) antibodies as its serological biomarkers. However, conve...
Ultrasensitive, Selectivity Detection of Mercury Ion Using a Novel Localized Surface Plasmon Resonance Biosensor.
Mercury ion, a highly toxic and bioaccumulative heavy metal pollutant, poses significant risks to human health and ecosystems even at trace concentrations. Therefore, ...
Emerging Trends in Artificial Intelligence-Integrated Biochip Technologies for Biomedical Applications.
Neurological disorders, diabetes, cancer, and infectious diseases remain major global health concerns, particularly in low- and middle-income countries with insufficie...
Optical Biosensors-Principles of Operation and Applications.
Biosensors have a recognition element that detects a bioanalyte as well as a transducer that transfers the measured physicochemical properties into an electric signal,...
Artificial Intelligence-Enabled Bioengineering of Extracellular Vesicle Platforms in Cardiovascular Medicine.
Extracellular vesicles (EVs) hold significant potential in cardiovascular diagnosis and treatment. However, their clinical applications are limited by challenges such ...
In Vitro Evaluation of GLP-1R-Associated Activity of a Sustainable Standardized Phospholipid-Formulated Bergamot Extract.
Background: Metabolic syndrome is characterized by dysregulated glucose metabolism and is a major risk factor for type 2 diabetes mellitus and cardiovascular disease. ...
DNA Electrochemical Sensor Based on Exonuclease III-Assisted Cycling Signal Amplification for Ultrasensitive Detection of Genetically Modified Soybean.
The safety of genetically modified crops, particularly the commercial cultivation of glyphosate-resistant genetically modified soybeans, has given rise to significant ...
Laser-Scribed Graphene on PDMS for Flexible Wearable Sweat Biosensors with Multiplexed Sensing Capability.
Sweat is a valuable biofluid for non-invasive health monitoring, as it contains electrolytes, metabolites, and organic compounds that can correlate with blood levels, ...