1415 条结果

Gradient method for accurate affinity determinations.

Analytical biochemistry 2023 Schasfoort RBM

The value of the affinity constants (kd, ka, and KD) that are determined by label free interaction analysis methods are strongly affected by the ligand density at the ...

The piperazine analogue para-fluorophenylpiperazine alters timing of the physiological effects of the synthetic cannabinoid receptor agonist AMB-FUBINACA, without changing its discriminative stimulus, signalling effects, or metabolism.

Pharmacology, biochemistry, and behavior 2023 Finlay DB, Mackie W, Webb HDJ, Thomsen LR 等 9 人

AMB-FUBINACA is a synthetic cannabinoid receptor agonist (SCRA), which has been associated with substantial abuse and health harm since 2016 in many countries includin...

Short Activators and Repressors of RNA Toehold Switches.

ACS synthetic biology 2023 McSweeney MA, Zhang Y, Styczynski MP

RNA toehold switches are a widely used class of molecule to detect specific RNA "trigger" sequences, but their design, intended function, and characterization to date ...