An electrochemical biosensor for sensitive analysis of the SARS-CoV-2 RNA.
The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is continuously worsening globally, here...
Label-free tracking of whole-cell response on RGD functionalized surfaces to varied flow velocities generated by fluidic rotation.
Fluidic flow plays important roles in colloid and interface sciences. Measuring adsorption, aggregation processes and living cell behavior under a fluidic environment ...
A novel tool for the adsorption of dsDNA: Electrochemical reduction of Pd nanoparticles onto reduced-keratin particles extracted from wool wastes.
This work outlines the fabrication of a novel electrochemical platform for the dsDNA adsorption, using one of the most sustainable materials, wool fabric waste, and Pd...
Improved production of human hemoglobin in yeast by engineering hemoglobin degradation.
Construction of 3D Bi/ZnSnO
Herein, we reported a label-free and reliable photoelectrochemical (PEC) platform for highly selective monitoring of norepinephrine (NE) based on metallic Bi nanoparti...
Using Biosensors to Study Protein-Protein Interaction in the Hippo Pathway.
The Hippo signaling network is dependent on protein-protein interactions (PPIs) as a mechanism of signal transduction to regulate organ size, cellular proliferation an...
Implementing radical cure diagnostics for malaria: user perspectives on G6PD testing in Bangladesh.
BACKGROUND: The radical cure of Plasmodium vivax requires treatment with an 8-aminoquinoline drug, such as primaquine and tafenoquine, to eradicate liver hypnozoite st...
Universal and Programmable Rolling Circle Amplification-CRISPR/Cas12a-Mediated Immobilization-Free Electrochemical Biosensor.
The development of a sensing platform with high sensitivity and specificity, especially programmability and universal applicability, for the detection of clinically re...
Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery.
We reported a proof-of-concept study of developing an electrochemical biosensor for prolonged continuous monitoring free flap failure caused by vascular occlusion afte...
Aptamer-based lateral flow assay on-site biosensors.
The lateral flow assay (LFA) is a widely used paper-based on-site biosensor that can detect target analytes and obtain test results in several minutes. Generally, anti...
High-Throughput Screening of an Octanoic Acid Producer Strain Library Enables Detection of New Targets for Increasing Titers in
Octanoic acid is an industrially relevant compound with applications in antimicrobials or as a precursor for biofuels. Microbial biosynthesis through yeast is a promis...
Molecule-Specific Terahertz Biosensors Based on an Aptamer Hydrogel-Functionalized Metamaterial for Sensitive Assays in Aqueous Environments.
Metamaterial-inspired terahertz (THz) biosensors are devoted to developing high-sensitivity and label-free biosensing strategies. However, most meaningful molecular si...
Engineering Bacteria to Monitor the Bleeding of Animals Using Far-Red Fluorescence.
Microorganisms living in animals can function as drug delivery systems or as detectors for some diseases. Here, we developed a biosensor constructed by the deletion of...
Proximity-induced exponential amplification reaction triggered by proteins and small molecules.
We proposed a method to regulate nucleic acid polymerization by proximity and designed an ultrasensitive biosensor based on proximity-induced exponential amplification...
A fluorescence-based yeast sensor for monitoring acetic acid.
Accumulation of acetic acid indicates an imbalance of the process due to a disturbed composition of the microorganisms. Hence, monitoring the acetic acid concentration...
An exonuclease protection and CRISPR/Cas12a integrated biosensor for the turn-on detection of transcription factors in cancer cells.
Transcription factors (TFs) are critical proteins that regulate the expression of genes, and the abnormal change of TFs levels is directly related to physical dysfunct...
Ultrasensitive electrochemical detection of miRNA coupling tetrahedral DNA modified gold nanoparticles tags and catalyzed hairpin assembly.
MicroRNAs (miRNAs) play key regulatory roles in a number of biological processes, which act as critical biomarkers for clinical diagnosis. There are urgent needs to de...
A novel colorimetric aptasensor for ultrasensitive detection of aflatoxin M
Colorimetric approaches have received noticeable attention among sensing methods in view of simplicity and watching the color change of sample by the naked eyes. Howev...
Tunable Multiplexed Whole-Cell Biosensors as Environmental Diagnostics for ppb-Level Detection of Aromatic Pollutants.
Aromatics such as phenols, benzene, and toluene are carcinogenic xenobiotics which are known to pollute water resources. By employing synthetic biology approaches comb...
A label-free fluorescent biosensor based on a catalyzed hairpin assembly for HIV DNA and lead detection.
Herein, a label-free fluorescent signal amplification system based on a catalyzed hairpin assembly (CHA) is reported. In this system, two hairpin probes, H1 and H2, we...