Thyroxine (T4) is a key hormone regulating metabolic, cardiovascular, and neurodevelopmental processes, yet its clinical quantification still relies on centralized imm...
Spirometry is widely regarded as the clinical gold standard for quantifying lung function. It plays a central role in the diagnosis and management of cardiopulmonary d...
Alzheimer's disease (AD) seriously affects human health worldwide. Nicotinamide adenine dinucleotide (NADH) and glutamate are important biomarkers of AD, which play an...
Psychosis presents significant treatment challenges, and standard Cognitive Behavioral Therapy for psychosis often faces limitations due to patient engagement issues a...
The development of highly sensitive and reliable strategies for microcystin-LR (MC-LR) monitoring remains critical for environmental safety and public health protectio...
Accurate monitoring of respiratory rates is critical for early detection of a range of clinical conditions. However, standard manual counting or inadequate clinical mo...
Oral diseases remain highly prevalent worldwide and require early diagnosis and continuous monitoring to improve clinical outcomes. Conventional diagnostic methods are...
Nitrate (NO3-) serves as a pivotal molecule with dual functions in nutrient supply and signaling during plant growth and development. Precise monitoring of its spatiot...
Chimeric antigen receptor (CAR) T-cell therapy is an effective treatment for hematologic malignancies. However, it is limited by high costs, risk of severe toxicities ...
Carotid artery disease, including atherosclerotic stenosis and non-atherosclerotic abnormalities, substantially increases ischemic stroke risk and motivates accessible...
The increasing use of antibiotics around the globe has contributed to an increase in antimicrobial resistance and become a major risk to both public health and sustain...
Metabolic homeostasis has been studied primarily at the tissue and organism level, identifying molecular control mechanisms such as the energy charge-sensing kinase AM...
BACKGROUND AND AIMS: Overdose induced by illicit drug use is a significant public health threat in many settings globally. Many such overdoses occur in the context of ...
Hydrogel-based biosensors offer a promising platform for designing microneedles capable of continuously tracking biomarkers in real time. However, such biosensors have...
This study introduces the development of a next-generation wearable biosensor for non-invasive glucose monitoring in human sweat, leveraging the unique properties of a...
Autophagy, a vital catabolic process, plays a crucial role in maintaining pancreatic β cell function and is disrupted in established type 1 diabetes. However, it is un...
Colorectal cancer (CRC) is frequently diagnosed at advanced stages due to the asymptomatic nature of early disease and the semi-invasive nature of colonoscopy. Develop...
The assembly of tau into amyloid filaments is associated with more than 20 neurodegenerative diseases, collectively termed tauopathies. Electron cryo-microscopy (cryo-...
Calcium-activated proteases, known as calpains, cleave proteins into smaller protein fragments, altering protein structure and function. Calpain overactivity is a path...