Commercial hydrogels for biomedical applications.
Hydrogels are polymeric networks having the ability to absorb a large volume of water. Flexibility, versatility, stimuli-responsive, soft structure are the advantages ...
Toward a point-of-care diagnostic for specific detection of Mycobacterium tuberculosis from sputum samples.
This study reports the development of a new PCR-free device, using IS6110 gene as biomarker, for Tuberculosis (TB) diagnosis. An arginine film (ARGFILM) was used to pr...
Dynamic light scattering biosensing based on analyte-induced inhibition of nanoparticle aggregation.
A new approach to direct quantitative detection of small molecules (haptens) by dynamic light scattering biosensing is presented. The proposed technique implements a h...
Electrochemical determination of zearalenone using a label-free competitive aptasensor.
An electrochemical aptasensor is described for determination of the phytohormone of zearalenone (ZEA). The gold electrode was modified with ZEA via covalent attachment...
Flex-GO (Flexible graphene oxide) sensor for electrochemical monitoring lactate in low-volume passive perspired human sweat.
In this work, a low volume, sweat lactate sensor functioning on passively expressed eccrine sweat was designed, fabricated and tested in human sweat and its performanc...
Execution of aggregation-induced emission as nano-sensors for hypochlorite detection and application for bioimaging in living cells and zebrafish.
Hypochlorite (ClO-) could be used as a diagnostic marker for inflammation and related diseases. Although there have been many reports on probes for ClO- imaging, there...
Highly sensitive and selective aflatoxin B
The biosensors based on aptamer based stimuli-responsive hydrogels have the characters of high specificity, good stability, portability. Electronic balance is one of t...
A nature-inspired colorimetric and fluorescent dual-modal biosensor for exosomes detection.
As non-invasive biomarkers, exosomes are of great significance to diseases diagnosis. However, sensitive and accurate detection of exosomes still remains technical cha...
Fast, sensitive and selective determination of herbicide glyphosate in water samples with a White Light Reflectance Spectroscopy immunosensor.
An optical immunosensor based on White Light Reflectance Spectroscopy is described for the determination of the herbicide glyphosate in drinking water samples. The bio...
Aptamer-based biosensor for detecting carcinoembryonic antigen.
Carcinoembryonic antigen (CEA), as one of the common tumor markers, is a human glycoprotein involved in cell adhesion and is expressed during human fetal development. ...
An ultrasensitive label-free colorimetric biosensor for the detection of glucose based on glucose oxidase-like activity of nanolayered manganese-calcium oxide.
During the last years, enzyme-based biosensors have gained much more attention among the researchers and have had great success in the determination of different biolo...
Core-satellite assemblies and exonuclease assisted double amplification strategy for ultrasensitive SERS detection of biotoxin.
In this work, core-satellite assemblies and exonuclease assisted double amplification strategy is developed to produce surface-enhanced Raman scattering (SERS) biosens...
Characterizations of protein-ligand reaction kinetics by transistor-microfluidic integrated sensors.
Understanding the binding affinities and kinetics of protein-ligand interactions using a label-free method is crucial for identifying therapeutic candidates in clinica...
Synthesis of water soluble CuGaS
Developing monitoring technique for alkaline phosphatase (ALP) is crucial due to the important role it plays in living cells. Here, a kind of biocompatible glutathione...
Disconnect between signalling potency and in vivo efficacy of pharmacokinetically optimised biased glucagon-like peptide-1 receptor agonists.
OBJECTIVE: The objective of this study was to determine how pharmacokinetically advantageous acylation impacts on glucagon-like peptide-1 receptor (GLP-1R) signal bias...
Directed evolution of a transcription factor PbrR to improve lead selectivity and reduce zinc interference through dual selection.
Directed evolution has been proven as a powerful tool for developing proteins and strains with novel or enhanced features. In this study, a dual selection system was d...
A three-dimensional DNA nanomachine with target recycling amplification technology and multiple electrochemiluminescence resonance energy transfer for sensitive microRNA-141 detection.
An electrochemiluminescence (ECL) three-dimensional (3D) DNA nanomachine is developed for microRNA-141 (miRNA-141) detection by coupling Pb2+ dependent DNAzyme assiste...
Hierarchical 0D-2D bio-composite film based on enzyme-loaded polymeric nanoparticles decorating graphene nanosheets as a high-performance bio-sensing platform.
Herein, we developed a hierarchical bio-composite sensing film by facile one-step electro-deposition of 0D enzyme-polymer nanoparticles (NPs) with 2D graphene oxide na...
Three-dimensional donor-acceptor-type photoactive material/conducting polyaniline hydrogel complex for sensitive photocathodic enzymatic bioanalysis.
Herein, an innovative photocathodic enzymatic biosensor is proposed with poly {4,8-bis[5-(2-ethylhexyl)thiophen-2-yl]-benzo[1,2-b:4,5-b']dithiophene-2,6-diyl-alt-3-flu...
Simple approach for the rapid estimation of BOD
A simple approach was developed for the rapid and accurate estimation of 5-day biochemical oxygen demand (BOD5) in food processing wastewater. Immobilization of the na...