3D hollow-out TiO
Ultra-high sensitivity is difficult to achieve using conventional enzymatic glucose biosensors due to the lack of exposed active sites and steric-hinderance effects. T...
PEGylated Bilirubin-coated Iron Oxide Nanoparticles as a Biosensor for Magnetic Relaxation Switching-based ROS Detection in Whole Blood.
Rationale: Magnetic relaxation switching (MRSw) induced by target-triggered aggregation or dissociation of superparamagnetic iron oxide nanoparticles (SPIONs) have bee...
Booster, a Red-Shifted Genetically Encoded Förster Resonance Energy Transfer (FRET) Biosensor Compatible with Cyan Fluorescent Protein/Yellow Fluorescent Protein-Based FRET Biosensors and Blue Light-Responsive Optogenetic Tools.
Genetically encoded Förster resonance energy transfer (FRET)-based biosensors have been developed for the visualization of signaling molecule activities. Currently, mo...
Differential activation of G protein-mediated signaling by synthetic cannabinoid receptor agonists.
Synthetic cannabinoid receptor agonists (SCRAs) are new psychoactive substances associated with acute intoxication and even death. However, the molecular mechanisms th...
Application of electrochemical biosensors in tumor cell detection.
Conventional methods for detecting tumors, such as immunological methods and histopathological diagnostic techniques, often request high analytical costs, complex oper...
Rapid screening and quantitative detection of Salmonella using a quantum dot nanobead-based biosensor.
The continuing hurdle of developing foodborne pathogen detection techniques is that compromises must be made among simplicity, portability, speed, sensitivity, and qua...
Simulation of an electrically actuated cantilever as a novel biosensor.
Recently, detecting biological particles by analyzing their mechanical properties has attracted increasing attention. To detect and identify different bioparticles and...
Quantum Dot Lipase Biosensor Utilizing a Custom-Synthesized Peptidyl-Ester Substrate.
Lipases are an important class of lipid hydrolyzing enzymes that play significant roles in many aspects of cell biology and digestion; they also have large roles in co...
Not So Dry After All: DRY Mutants of the AT1
G-protein-coupled receptors (GPCRs) are seven transmembrane spanning receptors that regulate a wide array of intracellular signaling cascades in response to various st...
Elucidating the Electrochemical Mechanism of NG-Hydroxy-L-arginine.
NG-Hydroxy-L-arginine (NOHA) is a stable intermediate product in the urea cycle that can be used to monitor the consumption of L-arginine by nitrous oxide synthase (NO...
Human primary endothelial label-free biochip assay reveals unpredicted functions of plasma serine proteases.
Tissue-on-a-chip technologies are more and more important in the investigation of cellular function and in the development of novel drugs by allowing the direct screen...
Lab-on-a-Chip Systems for Aptamer-Based Biosensing.
Aptamers are oligonucleotides or peptides that are selected from a pool of random sequences that exhibit high affinity toward a specific biomolecular species of intere...
Evaluation of the Oxidative Stress Response of Aging Yeast Cells in Response to Internalization of Fluorescent Nanodiamond Biosensors.
Fluorescent nanodiamonds (FNDs) are proposed to be used as free radical biosensors, as they function as magnetic sensors, changing their optical properties depending o...
Microfluidic-Based Biosensor for Blood Viscosity and Erythrocyte Sedimentation Rate Using Disposable Fluid Delivery System.
To quantify the variation of red blood cells (RBCs) or plasma proteins in blood samples effectively, it is necessary to measure blood viscosity and erythrocyte sedimen...
Reply to Comments: Comparison of Methods Study between a Photonic Crystal Biosensor and Certified ELISA to Measure Biomarkers of Iron Deficiency in Chronic Kidney Disease Patients.
In this brief note, we respond to the comments made by Dr [...].
Sustainable, Alginate-Based Sensor for Detection of
There are no existing affordable diagnostics for sensitive, rapid, and on-site detection of pathogens in milk. To this end, an on-site colorimetric-based sustainable a...
Comments on: "Comparison of Methods Study between a Photonic Crystal Biosensor and Certified ELISA to Measure Biomarkers of Iron Deficiency in Chronic Kidney Disease Patients".
We recently read, with great interest, the article entitled "Comparison of Methods Study between a Photonic Crystal Biosensor and Certified ELISA to Measure Biomarkers...
Novel superabsorbent biosensor nanohydrogel based on gum tragacanth polysaccharide for optical detection of glucose.
Effective biosensor devices for detection of glucose based on carbohydrate polymer nanohydrogels have been scarcely reported to date. In an attempt to construct a more...
A robust and efficient aqueous electrochemiluminescence emitter constructed by sulfonate porphyrin-based metal-organic frameworks and its application in ascorbic acid detection.
The robust and strong electrochemiluminescence (ECL) emission of organic emitters in an aqueous solution is crucial for expanding their applications in early diagnosis...
Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems.
Robust developments of personalized medicine for next-generation healthcare highlight the need for sensitive and accurate point-of-care platforms for quantification of...