Gd
In this work, we developed a multivalent magnetic biosensing strategy by integrating magnetic separation and magnetic relaxation switching (MRS) where Gd3+-loaded magn...
Switch-conversional ratiometric fluorescence biosensor for miRNA detection.
MicroRNAs play a crucial role in regulating gene expression and cellular function. Reliable detection of miRNA is highly demanded in clinical diagnosis and therapy. He...
Restriction of intramolecular motions (RIM) by metal-organic frameworks for electrochemiluminescence enhancement:2D Zr
Herein, a new phenomenon of enhanced electrochemiluminescence (ECL) emission by restricting intramolecular motion in the 2D ultra-thin Zr12-adb (adb = 9,10-anthracene ...
Nano-biosensor for the in vitro lactate detection using bi-functionalized conducting polymer/N, S-doped carbon; the effect of αCHC inhibitor on lactate level in cancer cell lines.
A robust amperometric sensor was developed for the lactate detection in the extracellular matrix of cancer cells. The sensor was fabricated by separately immobilizing ...
Engineered Sensor Zebrafish for Fast Detection and Real-Time Tracking of Apoptosis at Single-Cell Resolution in Live Animals.
Apoptosis plays crucial roles during development and in disease conditions. While there are some methods to detect apoptosis in vitro, most of them are end-point assay...
UV-Laser Interference Lithography for Local Functionalization of Plasmonic Nanostructures with Responsive Hydrogel.
A novel approach to local functionalization of plasmonic hotspots at gold nanoparticles with biofunctional moieties is reported. It relies on photocrosslinking and att...
Lateral flow assay using aptamer-based sensing for on-site detection of dopamine in urine.
A lateral flow assay using DNA aptamer-based sensing for the detection of dopamine in urine is reported. Dopamine duplex aptamers (hybridized sensor with capture probe...
Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts.
Cartilage acidic protein 1 (CRTAC1) is an extracellular matrix protein of human chondrogenic tissue that is also present in other vertebrates, non-vertebrate eukaryote...
Electrochemiluminescence resonance energy transfer between luminol and black phosphorus nanosheets for the detection of trypsin via the "off-on-off" switch mode.
In this work, the electrochemiluminescence (ECL) behavior of a luminol-H2O2 system was studied on a black phosphorus nanosheet (BPN) modified electrode. A quenching ef...
Paper-based colorimetric biosensor of blood alcohol with in-situ headspace separation of ethanol from whole blood.
This work presents a novel development that exploits the concept of in-situ gas-separation together with a specific enzymatic colorimetric detection to produce a porta...
Rapid Assessment of Surface Markers on Cancer Cells Using Immuno-Magnetic Separation and Multi-frequency Impedance Cytometry for Targeted Therapy.
The rapid qualitative assessment of surface markers on cancer cells can allow for point-of-care prediction of patient response to various cancer drugs. Preclinical stu...
Application of the cellular oxidation biosensor to Toxicity Identification Evaluations for high-throughput toxicity assessment of river water.
Toxicity Identification Evaluation (TIE) is a useful method for the classification and identification of toxicants in a composite environment water sample. However, it...
A New Biosensor for Stilbenes and a Cannabinoid Enabled by Genome Mining of a Transcriptional Regulator.
In vivo biosensors are powerful tools for metabolic engineering and synthetic biology applications. However, the development of biosensors is hindered by the limited n...
Design and Optimization of a Cell-Free Atrazine Biosensor.
Recent advances in cell-free synthetic biology have spurred the development of in vitro molecular diagnostics that serve as effective alternatives to whole-cell biosen...
Avian Influenza Virus Detection by Optimized Peptide Termination on a Boron-Doped Diamond Electrode.
The development of a simple detection method with high sensitivity is essential for the diagnosis and surveillance of infectious diseases. Previously, we constructed a...
The Antibody-Free Recognition of Cancer Cells Using Plasmonic Biosensor Platforms with the Anisotropic Resonant Metasurfaces.
It is vital and promising for portable and disposable biosensing devices to achieve on-site detection and analysis of cancer cells. Although traditional labeling techn...
An Improved ATP FRET Sensor For Yeast Shows Heterogeneity During Nutrient Transitions.
Adenosine 5-triphosphate (ATP) is the main free energy carrier in metabolism. In budding yeast, shifts to glucose-rich conditions cause dynamic changes in ATP levels, ...
Graphene/aptamer probes for small molecule detection: from in vitro test to in situ imaging.
Small molecules are key targets in molecular biology, environmental issues, medicine and food industry. However, small molecules are challenging to be detected due to ...
Screen-printed electrochemical biosensor based on a ternary Co@MoS
In this study, cobalt oxides functionalized MoS2/reduced graphene oxide was synthesized via a facile one-pot hydrothermal approach. Morphology and crystal structure of...
Amperometric biogenic amine biosensors based on Prussian blue, indium tin oxide nanoparticles and diamine oxidase- or monoamine oxidase-modified electrodes.
Biogenic amine biosensors, based on screen-printed carbon electrodes (SPCE) modified with Prussian blue (PB) and indium tin oxide nanoparticles (ITONP), are reported. ...