Development of a Novel, Ultra-rapid Biosensor for the Qualitative Detection of Hepatitis B Virus-associated Antigens and Anti-HBV, Based on "Membrane-engineered" Fibroblast Cells with Virus-Specific Antibodies and Antigens.
本文报道一种用于检测乙型肝炎病毒(HBV)相关抗原和抗HBV的新型微型细胞生物传感器。该传感器基于“膜工程”改造的Vero成纤维细胞,并将其固定于海藻酸基质中。膜工程通过电脉冲将HBV特异性抗体(anti-HBs、anti-HBe)或抗原(HBsAg)插入Vero细胞膜。当同源抗原与电插入抗体结合,或抗体与电插入抗原结合时,细胞膜电...