3 条结果 关键词:利什曼原虫 ×

Optimized DNA-based biosensor for monitoring Leishmania infantum in human plasma samples using biomacromolecular interaction: a novel platform for infectious disease diagnosis.

Analytical methods : advancing methods and applications 2020 Farshchi F, Saadati A, Hasanzadeh M

利什曼原虫鉴定对利什曼病临床诊断至关重要。传统方法存在局限,亟需灵敏、特异的检测技术。为实现选择性快速检测,本研究制备了一种新型纸基传感器:将银纳米棱镜(Ag NPr)电沉积在石墨烯量子点(GQDs)导电纳米墨水(Ag NPr/GQDs nano-ink)上,并通过电沉积半胱胺功能化金纳米粒子(AuNPs-CysA)构建高比表面积、...

An impedimetric genosensor for Leishmania infantum based on electrodeposited cadmium sulfide nanosheets.

Talanta 2020 Nazari-Vanani R, Heli H, Sattarahmady N

内脏利什曼病每年新增病例约40万,死亡约3万,因此快速准确检测婴儿利什曼原虫及其种属对公共卫生至关重要。本研究建立了一种基于DNA的基因传感器,用于检测婴儿利什曼原虫基因组DNA。该传感器以电沉积硫化镉纳米片(CdS nanosheets, CSN)为换能层,以特定单链DNA探针为识别元件,采用无标记、无标记物、无标签且无需PCR扩...

Binding of Leishmania spp with gold nanoparticles supported polyethylene glycol and its application for the sensitive detection of infectious photogenes in human plasma samples: A novel biosensor.

Journal of molecular recognition : JMR 2020 Mobed A, Mehri P, Hasanzadeh M, Mokhtarzadeh A

病原体快速、低成本检测对生物安全至关重要。内脏利什曼病(VL,黑热病)是利什曼原虫感染最严重类型,延误诊断和治疗可致死。尽管已有多种常规方法,仍需现代高灵敏检测系统。本研究制备了一种新型超灵敏 DNA 生物传感器,用于检测利什曼原虫(Leishmania spp)。首次通过电化学方法识别利什曼原虫基因组的特异性巯基化序列(5′-SH...