Tea polyphenols as an antivirulence compound Disrupt Quorum-Sensing Regulated Pathogenicity of Pseudomonas aeruginosa.
绿茶是未发酵茶叶的水提物,具有多种生物活性。本研究考察茶多酚(TP)作为抗毒力化合物在体外和体内抑制群体感应(QS)的潜力。生物传感器法显示,TP 对受试病原菌的最低抑菌浓度(MIC)为 6.25–12.5 mg/mL。在亚 MIC 浓度下,TP 可特异性抑制 Chromobacterium violaceum 12472 产生 v...