1 条结果 关键词:钙网蛋白 ×

Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle.

Proceedings of the National Academy of Sciences of the United States of America 2017 Manno C, Figueroa LC, Gillespie D, Fitts R 等 7 人

钙网蛋白(calsequestrin, Casq)是肌浆网(SR)中唯一已知以周期性储存和释放钙为主要功能的蛋白。为检验其在活细胞中是否随钙耗竭而去聚合,作者在小鼠肌肉中表达荧光标记 Casq1,并用与 Casq1 融合的钙生物传感器 D4cpV-Casq1 连续测量 SR 内钙浓度,同时以光漂白后荧光恢复(FRAP)监测 Casq...