Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.

亲电性外源物与氧化应激内源产物可诱导谷胱甘肽S-转移酶（GSTs）等II期解毒酶，从而清除内外应激；在不产生不良反应的前提下诱导II期酶可能有助于延缓衰老并维持健康。本文以山葵功能成分烯丙基异硫氰酸酯（AITC）为候选食品成分，检验其能否诱导GST而不损害动物生命。作者构建 gst::gfp 融合基因并转化秀丽隐杆线虫（C. ele...