Detection of DNA molecules and possible chemotherapy-induced changes in its structure has been the goal of researchers using rapid, sensitive and inexpensive approache...
In recent years, a huge number of individuals all over the world, elderly people, in particular, have been suffering from Alzheimer's disease (AD), which has had a sig...
Human fibrotic diseases constitute a major health problem worldwide. Fibrosis involves significant etiological heterogeneity and encompasses a wide spectrum of disease...
Itaconate is a newly discovered endogenous metabolite promoting an anti-inflammatory program during innate immune response, but the precise mechanisms underlying its e...
Detection of neurotransmitters at the single-cell level is essential for understanding the related biological processes and neurodegenerative diseases. We report a dua...
Foodborne or water-borne pathogens pose great threats to human beings and animals. There is an urgent need to detect pathogens with cheap, rapid and sensitive point-of...
Microneedles provide unique advantages in biomedical areas, particularly biosensing, because of their opportunities for minimally invasive and convenient detection. Th...
The high incidence of tuberculosis (TB) infection is of great concern world-wide. The traditional TB diagnostic techniques are not ideal for TB diagnosis in resource-p...
Enzyme-based amperometric biosensors represent powerful tools for remote medicine and in situ analysis. Nowadays, billions of people are surrounded by enzyme-based amp...
At the end of 2019, the novel coronavirus disease 2019 (COVID-19), a cluster of atypical pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-...
Polymer dots (Pdots) as electrochemiluminescence (ECL) emitters have drawn intensive attention for expanding the application of ECL analytical technology. Here we used...
Engineered light, oxygen, and voltage (LOV)-based proteins are able to fluoresce without oxygen requirement due to the autocatalytic incorporation of exogenous flavin ...
This work presents a theoretical verification for the detection of Sodium iodide (NaI) solution with different concentrations in the vicinity of Tamm plasmon (TP) reso...
The identification of tumor-related microRNAs (miRNAs) exhibits excellent promise for the early diagnosis of cancer and other bioanalytical applications. Therefore, we...
Hyaluronic Acid (HA) is a non-sulfated glycosaminoglycan, which is a potential biomarker that could be evaluated in the diagnosis of some cancers. For the first time, ...
Gold nanoparticles (AuNPs) in aggregated state have a strong near infrared region (NIR) absorption and the causes a much stronger photothermal effect than that of the ...
Production of therapeutic monoclonal antibodies (mAbs) is a complex process that requires extensive analytical and bioanalytical characterization to ensure high and co...
To address the urgent demand for sensitive and stable detection applications, significant efforts have been made in the development of dual-signal readout assays for p...
Gene biomarkers of circulating tumor DNA (ctDNA) in liquid biopsies have been explored for use in the precise diagnosis of tumors. There is a great clinical need to re...