Phase-segregated Membrane Model assessed by a combined SPR-AFM Approach.
Model biomembranes can provide valuable insights into the properties of complex biological membranes. Among several techniques, Surface Plasmon Resonance (SPR) provide...
Molecular architecture for DNA wiring.
Detection of the hybridisation events is of great importance in many different biotechnology applications such as diagnosis, computing, molecular bioelectronics, and a...
An electrochemical strategy with tetrahedron rolling circle amplification for ultrasensitive detection of DNA methylation.
Sensitive and specific detection of DNA methylation in genomic DNA is imperative for rapid epigenetic evaluations. Here, a novel sensitive electrochemical strategy was...
Electrochemical biosensor based on Se-doped MWCNTs-graphene and Y-shaped DNA-aided target-triggered amplification strategy.
A highly sensitive electrochemical biosensor for detection of platelet-derived growth factor-BB (PDGF-BB) is developed by using Se-doped multi-walled carbon nanotubes ...
Development of novel portable and reusable fiber optical chemiluminescent biosensor and its application for sensitive detection of microcystin-LR.
A novel portable fiber optical chemiluminescent biosensor (FOCB) system was successfully constructed using fiber optic bio-probe as biorecognition element as well as t...
Dual triggers induced disassembly of DNA polymer decorated silver nanoparticle for ultrasensitive electrochemical Pb
In this work, a new label-free biosensor based on highly effective decomposition of a branched DNA polymer and target-transition recycling amplification was designed f...
Electrochemical biosensor made with tyrosinase immobilized in a matrix of nanodiamonds and potato starch for detecting phenolic compounds.
The envisaged ubiquitous sensing and biosensing for varied applications has motivated materials development toward low cost, biocompatible platforms. In this paper, we...
Rational construction of a DNA nanomachine for HIV nucleic acid ultrasensitive sensing.
HIV nucleic acids, one kind of significant biomarker, play an important role in fundamental studies and clinical diagnosis. Importantly, the early accurate diagnosis f...
Development of a Metabolite Sensor for High-Throughput Detection of Aldehydes in
We have developed a fluorescence-based metabolite sensor enabling in vivo detection of various aldehydes of biotechnological interest in Escherichia coli. YqhC is a tr...
Aluminum plasmonic waveguides co-integrated with Si
Co-integrating CMOS plasmonics and photonics became the "sweet spot" to hit in order to combine their benefits and allow for volume manufacturing of plasmo-photonic in...
Simultaneous Detection of Hydroquinone and Catechol Using Platinum Nanoparticles Decorated Graphene/Poly-Cyclodextrin/Multiwalled Carbon Nanotubes (MWCNTs) Nanocomposite Based Biosensor.
Graphene cyclodextrin prepolymer (pre-CD)-multiwall carbon nanotubes (Gr-CDP-MWCNTs) nanocomposites modified on glassy carbon electrode (Gr-CDP-MWCNTs/GCE) are prepare...
A Novel Fluorescent Biosensor for Adenosine Triphosphate Detection Based on a Metal⁻Organic Framework Coating Polydopamine Layer.
In this work, a novel and sensitive fluorescent biosensor based on polydopamine coated Zr-based metal⁻organic framework (PDA/UiO-66) is presented for adenosine triphos...
Use of hafnium(IV) oxide in biosensors.
Hafnium(IV) oxide is a material with properties that can increase the sensitivity, durability, and reliability of biosensors made from silicon dioxide and other semico...
5-Methylcytosine containing CG decamer as Z-DNA embedded sequence for a potential Z-DNA binding protein probe.
Attempting to elucidate biological significance of the left-handed Z-DNA is a research challenge due to Z-DNA potential role in many diseases. Discovery of Z-DNA bindi...
Multiplex detection of urinary miRNA biomarkers by transmission surface plasmon resonance.
The clinical assessment of short-stranded nucleic acid biomarkers such as miRNAs could potentially provide useful information for monitoring disease progression, promp...
MicroRNA Detection through DNAzyme-Mediated Disintegration of Magnetic Nanoparticle Assemblies.
DNA-assembled nanoparticle superstructures offer numerous bioresponsive properties that can be utilized for point-of-care diagnostics. Functional DNA sequences such as...
A novel mass spectrometry method based on competitive non-covalent interaction for the detection of biomarkers.
We report a novel biosensor platform based on competitive non-covalent interaction between ssDNA and a mass tag towards AuNPs, which detects PSA biomarkers sensitively...
Identification of inactive conformation-selective interleukin-2-inducible T-cell kinase (ITK) inhibitors based on second-harmonic generation.
Many clinically approved protein kinase inhibitors stabilize an inactive conformation of their kinase target. Such inhibitors are generally highly selective compared t...
Coumarin Reduces Virulence and Biofilm Formation in
As one of the major pathogens in wound infections, Pseudomonas aeruginosa produces several virulence factors and forms biofilms; these processes are under the regulati...
In Vitro Selection of Specific DNA Aptamers Against the Anti-Coagulant Dabigatran Etexilate.
Dabigatran Etexilate (PRADAXA) is a new oral anticoagulant increasingly used for a number of blood thrombosis conditions, prevention of strokes and systemic emboli amo...