Direct detection of microRNA in liquid biopsies from single cancer spheroids.
Exploring cancer heterogeneity is crucial for both understanding cancer and developing prognostic tools to monitor cancer progression during treatment through the liqu...
Development of G-Ag and C-Ag Nanoparticle-Based Biosensor for Benzoic Acid Detection.
In this study, an efficient electrochemical sensor for the highly sensitive detection of benzoic acid (BA) is developed using silver nanoparticles (Ag NPs) obtained by...
A low-power approach to optical glucose sensing via polarisation switching.
High-precision polarimetry is crucial for sensing and imaging applications, particularly for glucose monitoring within the physiological range of 50 to 400 mg/dl. Trad...
Optimizing microfluidic chip for rapid SARS-CoV-2 detection using Taguchi method and artificial neural network PSO.
Microfluidic biosensors offer a promising solution for real-time analysis of coronaviruses with minimal sample volumes. This study optimizes a biochip for the rapid de...
SGO2 does not play an essential role in separase inhibition during meiosis I in mouse oocytes.
During meiosis I in oocytes, anaphase is triggered by deactivation of cyclin B1-CDK1 and activation of separase. Active separase plays an essential role in cleaving co...
Advancing clinical biochemistry: addressing gaps and driving future innovations.
Modern healthcare depends fundamentally on clinical biochemistry for disease diagnosis and therapeutic guidance. The discipline encounters operational constraints, inc...
Engineering coupled consortia-based biosensors for diagnostic.
Synthetic multicellular systems have great potential for performing complex tasks, including multi-signal detection and computation through cell-to-cell communication....
Carbon microelectrodes for the measurement of neurotransmitters with fast-scan cyclic voltammetry: methodology and applications.
Carbon microelectrodes (CMEs) have emerged as pivotal tools in the field of neurochemical sensing, enabling precise, real-time monitoring of neurotransmitters in both ...
Reusable Turn-on Fluorescent Biosensor for Cardiac Biomarker Troponin I Detection Using QDs-SPION-Aptamer.
Tro ponin is a biomolecule found in the blood of humans that can be used as an indicator of cardiac damage and cardiovascular risk. In this study, a turn-on fluorescen...
Creation of a highly stable direct electron transfer-type enzyme sensor by combining a hyperthermophilic dehydrogenase and natural electron mediator.
This study aimed to address the stability limitations of third-generation biosensors using enzymes from mesophilic organisms, by engineering a stable direct electron t...
Kinetically Arrested SERS-Active Aggregates for Biosensing.
There is great demand for biosensors capable of long-term, non-invasive monitoring of low analyte concentrations in various biofluids for diagnostics, personalized hea...
The theory, technology, and application of terahertz metamaterial biosensors: A review.
Terahertz metamaterial biosensors combine terahertz time-domain spectroscopy with metamaterial sensing to provide a sensitive detection platform for a variety of targe...
Efficient detection of gastric cancer biomarkers on functionalized carbon nanoribbons using DFT analysis.
Early diagnosis of gastric cancer (GC) is crucially important to initiate a therapy plan aiming at rescue and cure. In this regard, the detection of volatile organic c...
Advances and applications of biosensors in pulmonary hypertension.
Pulmonary hypertension (PH) is a serious disease characterized by elevated pulmonary artery pressure, with its prevalence and incidence continuously increasing, posing...
The G protein modifier KCTD5 tunes the decoding of neuromodulatory signals necessary for motor function in striatal neurons.
G proteins (Gα and Gβγ subtypes) drive adenylyl cyclase type 5 (AC5) synthesis of cAMP in striatal neurons, which is essential for motor coordination. KCTD5 directly i...
Viral escape-inspired framework for structure-guided dual bait protein biosensor design.
A generalizable computational platform, CTRL-V (Computational TRacking of Likely Variants), is introduced to design selective binding (dual bait) biosensor proteins. T...
Determining physiological responses of mussels (
Intertidal bivalves survive longer without oxygen when aerially exposed during low tide than when submerged in hypoxic water. To understand this, we combined three bio...
Fabrication and Characterization of a Flexible Non-Enzymatic Electrochemical Glucose Sensor Using a Cu Nanoparticle/Laser-Induced Graphene Fiber/Porous Laser-Induced Graphene Network Electrode.
We demonstrate a flexible electrochemical biosensor for non-enzymatic glucose detection under different bending conditions. The novel flexible glucose sensor consists ...
Emerging Biomarkers and Electrochemical Biosensors for Early Detection of Premature Coronary Artery Disease.
Coronary artery disease (CAD) is one of the primary causes of morbidity and death worldwide. Premature CAD (pCAD) is the term used to describe the 3-10% of CAD occurre...
Wearable Technology in Gastroenterology: Current Applications and Future Directions.
Advances in wearable technology have revolutionized healthcare by enabling the continuous monitoring of patients and personalized healthcare delivery. In the field of ...