Polythiophene biosensor for rapid detection of microbial particles in water.
Most microbial particles have a negatively charged surface and in this work, we describe a water quality monitoring application of a cationic polythiophene derivative ...
In situ screening of 3-arylcoumarin derivatives reveals new inhibitors of mast cell degranulation.
Due to the severity and high prevalence of allergic diseases, there is growing interest in the development of inhibitors of such conditions. 3-Arylcoumarin derivatives...
Immobilization of glucose oxidase into a nanoporous TiO₂ film layered on metallophthalocyanine modified vertically-aligned carbon nanotubes for efficient direct electron transfer.
Glucose oxidase (GOD) was adsorbed into a nanoporous TiO₂ film layered on the surface of an iron phthalocyanine (FePc) vertically-aligned carbon nanotube (CNT) modifie...
Analysis of the interaction between tropomyosin allergens and antibodies using a biosensor based on imaging ellipsometry.
A biosensor based on high spatial resolution imaging ellipsometry has been studied to examine its role in the rapid detection and analysis of the tropomyosin allergen ...
Quantitative FRET imaging to visualize the invasiveness of live breast cancer cells.
Matrix metalloproteinases (MMPs) remodel tumor microenvironment and promote cancer metastasis. Among the MMP family proteases, the proteolytic activity of the pro-tumo...
Development of a biosensor for detection of pleural mesothelioma cancer biomarker using surface imprinting.
Hyaluronan-linked protein 1 (HAPLN1) which has been shown to be highly expressed in malignant pleural mesotheliomas (MPM), was detected in serum using an electrochemic...
Cationic poly(lactic-co-glycolic acid) iron oxide microspheres for nucleic acid detection.
Herein, we envisage the possibility of preparing stable cationic poly(lactic-co-glycolic acid) (PLGA) microspheres encapsulating the iron oxide nanoparticles (IONPs; 8...
Rapid detection of human immunodeficiency virus types 1 and 2 by use of an improved piezoelectric biosensor.
Disasters can create situations in which blood donations can save lives. However, in emergency situations and when resources are depleted, on-site blood donations requ...
Mapping a disordered portion of the Brz2001-binding site on a plant monooxygenase, DWARF4, using a quartz-crystal microbalance biosensor-based T7 phage display.
In small-molecule/protein interaction studies, technical difficulties such as low solubility of small molecules or low abundance of protein samples often restrict the ...
Impact of DNA sequence and oligonucleotide length on a polythiophene-based fluorescent DNA biosensor.
DNA hybridization is a universal and specific mechanism for the recognition of biological targets. Some cationic polythiophene transducers sensitive to DNA structure h...
Bacteria screening, viability, and confirmation assays using bacteriophage-impedimetric/loop-mediated isothermal amplification dual-response biosensors.
Here, we integrate two complementary detection strategies for the identification and quantification of Escherichia coli based on bacteriophage T4 as a natural biorecep...
Development of a plate-based optical biosensor fragment screening methodology to identify phosphodiesterase 10A inhibitors.
We describe the development of a novel fragment screening methodology employing a plate-based optical biosensor system that can operate in a 384-well format. The metho...
Highly sensitive grating coupler-based surface plasmon-coupled emission (SPCE) biosensor for immunoassay.
We have evaluated the performance of a novel high-content gold grating coupler-based surface plasmon-coupled emission (SPCE) biosensor system. The polyelectrolyte (PEL...
Highly sensitive localized surface plasmon resonance immunosensor for label-free detection of HIV-1.
UNLABELLED: A highly sensitive label-free immunosensor for the detection of HIV-1 is newly developed based on localized surface plasmon resonance (LSPR) method. Unifor...
Multi-labeled functionalized C₆₀ nanohybrid as tracing tag for ultrasensitive electrochemical aptasensing.
This work reports a new supramolecular method for the synthesis of the amino and thiol groups functionalized C₆₀ nanoparticles (FC60NPs) with the large surface active ...
Label-free, real-time interaction and adsorption analysis 2: quartz crystal microbalance.
In this chapter, a second biosensor technique is described: the quartz crystal microbalance (QCM). The quartz crystal microbalance is a physical technique that detects...
Label-free, real-time interaction and adsorption analysis 1: surface plasmon resonance.
A key requirement for the development of proteins for use in nanotechnology is an understanding of how individual proteins bind to other molecules as they assemble int...
Hydrogen peroxide biosensor based on hemoglobin immobilized at graphene, flower-like zinc oxide, and gold nanoparticles nanocomposite modified glassy carbon electrode.
In this work, a highly sensitive hydrogen peroxide (H2O2) biosensor based on immobilization of hemoglobin (Hb) at Au nanoparticles (AuNPs)/flower-like zinc oxide/graph...
Signal amplification aptamer biosensor for thrombin based on a glassy carbon electrode modified with graphene, quantum dots and gold nanoparticles.
A novel electrogenerated chemiluminescence (ECL) assay for sensitive determination of thrombin is designed employing CdSe/ZnS quantum dots served as an ECL label. This...
Increased sensitivity of SPR assays in plasma through efficient parallel assay optimization.
The sensitivity of biosensor assays in complex media such as plasma or serum is often limited by non-specific binding. The degree of binding often varies between indiv...