共 1315 条结果
Biosensors & bioelectronics
2014
Xue T, Cui X, Guan W, Wang Q 等 9 人
The binding of DNA with graphene oxide (GO) is important for applications in disease diagnosis, genetic screening, and drug discovery. The standard assay methods are m...
Analytical chemistry
2014
Chen X, Wang Y, Zhang Y, Chen Z 等 7 人
We demonstrate a multivalent recognition and highly selective aptamer signal amplification strategy for electrochemical cytosensing and dynamic cell surface N-glycan e...
Pharmacology research & perspectives
2014
Carter RL, Grisanti LA, Yu JE, Repas AA 等 9 人
Label-free systems for the agnostic assessment of cellular responses to receptor stimulation have been shown to provide a sensitive method to dissect receptor signalin...
Journal of pharmaceutical and biomedical analysis
2014
Fortugno C, Varchi G, Guerrini A, Carrupt PA 等 5 人
Bicalutamide (Casodex®) is a non-steroidal anti-androgen drug used in the treatment of prostate cancer, which represents the second most common malignancy diagnosed in...
IEEE transactions on biomedical circuits and systems
2014
Liu X, Li L, Mason AJ
Because many proteins useful in biosensors exhibit temperature dependent activity, this paper explores the opportunity to integrate thermal control within a protein ar...
IEEE transactions on biomedical circuits and systems
2014
Lim YC, Kouzani AZ, Duan W, Dai XJ 等 6 人
Biosensors based on microcantilevers convert biological recognition events into measurable mechanical displacements. They offer advantages such as small size, low samp...
IEEE transactions on biomedical circuits and systems
2014
MacKay S, Wishart D, Xing JZ, Chen J
Aptamers are, in general, easier to produce, easier to store and are able to bind to a wider variety of targets than antibodies. For these reasons, aptamers are gainin...
Biosensors & bioelectronics
2014
Sheng M, Gao Y, Sun J, Gao F
A novel composite film based on carbon nanodots (CNDs) and chitosan was readily prepared and used as immobilization matrix to entrap a heme protein, hemoglobin (Hb) fo...
International journal of biological macromolecules
2014
Pandiselvi K, Thambidurai S
In this study, inorganic-organic redox mediators of CS-ZnO/PANI nanocomposite were synthesized by simple precipitation and chemical polymerization approach in the pres...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
2014
Yu M, Wang W, Zhang N
Quinoline based fluorescence sensor (1) was synthesized and characterized with mass spectra (MS), ((1))H nuclear magnetic resonance (((1))H NMR) spectrometer, elementa...
Biotechnology journal
2014
Malm M, Bass T, Gudmundsdotter L, Lord M 等 7 人
Emerging strategies in cancer biotherapy include the generation and application of bispecific antibodies, targeting two tumor-associated antigens for improved tumor se...
Small (Weinheim an der Bergstrasse, Germany)
2014
Khatayevich D, Page T, Gresswell C, Hayamizu Y 等 6 人
Direct molecular detection of biomarkers is a promising approach for diagnosis and monitoring of numerous diseases, as well as a cornerstone of modern molecular medici...
Chemistry (Weinheim an der Bergstrasse, Germany)
2014
Sulmann S, Dell'Orco D, Marino V, Behnen P 等 5 人
Fundamental components of signaling pathways are switch modes in key proteins that control start, duration, and ending of diverse signal transduction events. A large g...
Nanomedicine : nanotechnology, biology, and medicine
2014
Tung YT, Wu MF, Wang GJ, Hsieh SL
UNLABELLED: In this paper, we develop an effective method for detecting weak molecular bonding between the dengue virus (DV) and its receptor C-type lectin domain fami...
Molecular microbiology
2014
McDonough E, Lazinski DW, Camilli A
Vibrio cholerae, the causative agent of cholera, remains a threat to public health in areas with inadequate sanitation. As a waterborne pathogen, V. cholerae moves bet...
Langmuir : the ACS journal of surfaces and colloids
2014
Ali MA, Kamil Reza K, Srivastava S, Agrawal VV 等 6 人
A label-free biosensor based on antiapolipoprotein B 100 functionalized-aminated reduced graphene oxide interface has been fabricated for detection of low density lipo...
Metallomics : integrated biometal science
2014
McCranor BJ, Szmacinski H, Zeng HH, Stoddard AK 等 8 人
Copper is a required trace element that plays key roles in a number of human enzymes, such that copper deficiency or genetic defects in copper transport lead to seriou...
Nanotechnology
2014
Xu S, Man B, Jiang S, Yue W 等 8 人
We demonstrate that continuous, uniform graphene films can be directly synthesized on quartz substrates using a two-temperature-zone chemical vapor deposition system a...
Biomedical microdevices
2014
Sarkar D, Gunda NS, Jamal I, Mitra SK
In this work, we have demonstrated an efficient optical immunoassay technique for the detection of a food-borne pathogen, Listeria monocytogenes, using a Mach-Zehnder ...
Optics express
2014
Choi JM, Eom K, Hwang S, Lee Y 等 7 人
We demonstrate the proof-of-concept for developing a multi-color fluorescence imaging system based on plasmonic wavelength selection and double illumination by white l...