Biosensor Applications of MAPLE Deposited Lipase.
Matrix Assisted Pulsed Laser Evaporation (MAPLE) is a thin film deposition technique derived from Pulsed Laser Deposition (PLD) for deposition of delicate (polymers, c...
Piezoelectric biosensors for organophosphate and carbamate pesticides: a review.
Due to the great amount of pesticides currently being used, there is an increased interest for developing biosensors for their detection. Among all the physical transd...
Biosensors with built-in biomolecular logic gates for practical applications.
Molecular logic gates, designs constructed with biological and chemical molecules, have emerged as an alternative computing approach to silicon-based logic operations....
Study of Paclitaxel-Treated HeLa Cells by Differential Electrical Impedance Flow Cytometry.
This work describes the electrical investigation of paclitaxel-treated HeLa cells using a custom-made microfluidic biosensor for whole cell analysis in continuous flow...
Use of a parasitic wasp as a biosensor.
Screening cargo for illicit substances is in need of rapid high-throughput inspection systems that accurately identify suspicious cargo. Here we investigate the abilit...
Recent advances in bioprinting and applications for biosensing.
Future biosensing applications will require high performance, including real-time monitoring of physiological events, incorporation of biosensors into feedback-based d...
A wrist-worn biosensor system for assessment of neurological status.
EEG based monitoring for the purpose of assessing a patient's neurological status is conspicuous and uncomfortable at best. We are analyzing a set of physiological sig...
An integrated passive-flow microfluidic biosensor with organic photodiodes for ultra-sensitive pathogen detection in water.
This work reports on integrated passive-flow optical microfluidic devices to detect waterborne pathogens in the field. Ring-shaped organic photodiodes were integrated ...
Development and initial testing of a novel slime mould biosensor.
A plurality of whole cell biosensors have been developed using many different cell types. Biosensors incorporate biomolecular components or whole cells to facilitate s...
Distributed feedback laser for biosensing applications.
We present an organic semiconductor distributed feedback laser biosensor and demonstrate its sensing capabilities. Optimization of the gain layer thickness to maximize...
Detection of protein-small molecule binding using a self-referencing external cavity laser biosensor.
High throughput screening of protein-small molecule binding interactions using label-free optical biosensors is challenging, as the detected signals are often similar ...
Protein-protein binding detection with nanoparticle photonic crystal enhanced microscopy (NP-PCEM).
We demonstrate a novel microscopy-based biosensing approach that utilizes a photonic crystal (PC) surface to detect protein-protein binding with the functionalized nan...
Electrochemical biochip for applications to wireless and batteryless monitoring of free-moving mice.
A multi-sensing platform for applications in wireless and batteryless monitoring of free-moving small animals is presented in this paper. The proposed platform hosts s...
Development and characterization of a diamond-insulated graphitic multi electrode array realized with ion beam lithography.
The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the devel...
The effects of endogenous non-peptide molecule isatin and hydrogen peroxide on proteomic profiling of rat brain amyloid-β binding proteins: relevance to Alzheimer's disease?
The amyloid-β peptide is considered as a key player in the development and progression of Alzheimer's disease (AD). Although good evidence exists that amyloid-β accumu...
Effect of channel length on the electrical response of carbon nanotube field-effect transistors to deoxyribonucleic acid hybridization.
A single-walled carbon nanotube (SWCNT) in a field-effect transistor (FET) configuration provides an ideal electronic path for label-free detection of nucleic acid hyb...
Rapid microfluidic solid-phase extraction system for hyper-methylated DNA enrichment and epigenetic analysis.
Genetic sequence and hyper-methylation profile information from the promoter regions of tumor suppressor genes are important for cancer disease investigation. Since hy...
Improving the binding efficiency of quartz crystal microbalance biosensors by applying the electrothermal effect.
A quartz crystal microbalance (QCM) serving as a biosensor to detect the target biomolecules (analytes) often suffers from the time consuming process, especially in th...
Visualization of cyclic nucleotide dynamics in neurons.
The second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) transduce many neuromodulatory signals from hormones and neurotra...
Refolded scFv antibody fragment against myoglobin shows rapid reaction kinetics.
Myoglobin is one of the early biomarkers for acute myocardial infarction. Recently, we have screened an antibody with unique rapid reaction kinetics toward human myogl...