共 25874 条结果
Frontiers in bioengineering and biotechnology
2025
McNeal TA, Weinberger J, Liman GLS, Ariagno TM 等 7 人
Inteins (intervening proteins) interrupt host proteins and are removed through a protein splicing reaction that ligates adjacent N- and C-exteins. The ability of intei...
ACS bio & med chem Au
2025
Ranzau BL, Robinson TD, Scully JM, Kapelczak ED 等 7 人
Malonyl-CoA is the essential building block of fatty acids and regulates cell function through protein malonylation and allosteric regulation of signaling networks. Ac...
RSC medicinal chemistry
2025
Jung J, Sung JS, Kwon S, Bae HE 等 8 人
Fv-antibodies targeting the transmembrane protease serine 2 (TMPRSS2) were screened from an Fv-antibody library for inhibiting SARS-CoV-2 infection. Fv-antibodies were...
Nature communications
2025
Chen Y, Li X, Yue X, Yu W 等 10 人
Synthetic drugs fundamentally reshape the illicit drug market due to their low cost, ease of production, and rapid manufacturing processes. However, current drug detec...
Heliyon
2025
Khalid A, Santhanam J, Tzar MN, Chua AL 等 8 人
OBJECTIVES: The diagnosis of invasive fungal diseases (IFDs) is time consuming and lacks sensitivity. In this research a rapid and easy to use immunochromatography-bas...
bioRxiv : the preprint server for biology
2025
Klein AH, Alam S, Johnson K, Kriner C 等 10 人
Prolonged exposure to Gαi/o receptor agonists such as opioids can lead to a sensitization of adenylyl cyclases (ACs), resulting in heterologous sensitization or cyclic...
Experimental hematology & oncology
2025
Caratelli S, De Paolis F, Silvestris DA, Baldari S 等 22 人
BACKGROUND: Recent studies have shown that CD32/CD8a/CD28/CD3ζ chimeric receptor cells directly kill breast cancer cells, suggesting the existence of cell surface myel...
Synthetic biology (Oxford, England)
2025
Vaccari NA, Zevallos-Aliaga D, Peeters T, Guerra DG
Many studies characterize transcription factors and other regulatory elements to control gene expression in recombinant systems. However, most lack a formal approach t...
ACS omega
2025
McCann B, Tipper B, Shahbeigi S, Soleimani M 等 6 人
There are challenges associated with design and development of affinity biosensors due to the complicated multiphysics nature of the system. Understanding the binding ...
Bioresources and bioprocessing
2025
Gebeyehu EK, Shresth R, Saha T, Tienaho J 等 7 人
The growing demand for antimicrobial textiles and environmental concerns over synthetic agents have driven interest in biobased agents like chitosan, an eco-friendly a...
Electrophoresis
2025
Leclerc CA, Ty CGD, Worthington SS, Richardson MB 等 8 人
This work describes a cross-shaped PMMA ME system capable of detecting ciprofloxacin hydrochloride monohydrate (CPFH) in unfiltered milk samples. The cross-shaped PMMA...
Frontiers in chemistry
2025
Zhang J, Ma C, Du Y, Huang J 等 5 人
Rapid detection of foodborne pathogenic bacteria is critical for ensuring food safety and preventing foodborne disease outbreaks. Traditional detection methods, while ...
Sensors (Basel, Switzerland)
2025
Pouriayevali M, McWilliams R, Bachar A, Atwal P 等 6 人
Breast cancer remains a leading cause of cancer-related deaths among women, emphasizing the critical need for early detection and monitoring techniques. Conventional i...
Molecules (Basel, Switzerland)
2025
Monkratok J, Janphuang P, Chansaenpak K, Lisnund S 等 6 人
We developed a membraneless-microfluidic biofuel cell (MBFC) for the quantification of ethanol. The system employs anolyte and catholyte solutions, each containing a b...
Molecules (Basel, Switzerland)
2025
Ma M, Zhang M, Wang J, Zhou Y 等 6 人
We present a lateral flow aptasensor for the visual detection of alpha-fetoprotein (AFP) in human serum. Leveraging the precise molecular recognition capabilities of a...
Molecules (Basel, Switzerland)
2025
Sist P, Urbani R, Tramer F, Bandiera A 等 5 人
HUG is the HELP-UnaG recombinant fusion protein featuring the typical functions of both HELP and UnaG. In HUG, the HELP domain is a thermoresponsive human elastin-like...
Materials (Basel, Switzerland)
2025
Huang J, Xie S, Fan H, Song C 等 9 人
In cell culture research and biotechnology, precise pH monitoring is crucial for maintaining cellular health and ensuring reliable experimental outcomes. Traditional p...
International journal of molecular sciences
2025
Li Y, Chen J, Yang C, Fan W 等 10 人
A novel photoelectrochemical (PEC) biosensor was proposed by preparing Au NP/MXene-BiOCl Moiré superlattice nanosheets as the probes. Upon irradiation with visible lig...
ACS nano
2025
Lin PY, Chang YF, Chen CC, Su LC 等 6 人
Bladder cancer (BC) has a high recurrence rate, necessitating frequent monitoring. We herein present an innovative method for detecting BC-related miR-183 and miR-155 ...
The Journal of cell biology
2025
Holmes VL, Ricci MMC, Weckerly CC, Worcester M 等 5 人
Genetically encoded lipid biosensors uniquely provide real time, spatially resolved kinetic data for lipid dynamics in living cells. Despite clear strengths, these too...