Litmus-Body: A Molecularly Targeted Sensor for Cell-Surface pH Measurements.
Precise pH measurements in the immediate environment of receptors is essential for elucidating the mechanisms through which local pH changes associated with diseased p...
Capping Ligand Size-Dependent LSPR Property Based on DNA Nanostructure-Mediated Morphological Evolution of Gold Nanorods for Ultrasensitive Visualization of Target DNA.
Systematically tuning the structures and properties of noble-metal nanoparticles through biomolecule-mediated overgrowth is of significant importance for their applica...
Structure Engineering of a Lanthanide-Based Metal-Organic Framework for the Regulation of Dynamic Ranges and Sensitivities for Pheochromocytoma Diagnosis.
Exploring innovative technologies to precisely quantify biomolecules is crucial but remains a great challenge for disease diagnosis. Unfortunately, the humoral concent...
First-Principles Insight into a Ru-Doped SnS
Realizing the diagnosis of lung cancer at an inchoate stage is significant to get valuable time to conduct curative surgery. In this work, we relied on a density funct...
Point-of-care testing of MicroRNA based on personal glucose meter and dual signal amplification to evaluate drug-induced kidney injury.
The upregulation or downregulation of microRNA-21 (miRNA-21) is closely related with drug-induced kidney injury (DIKI). As a potential and significant biomarker, the p...
Accuracy improvement of electrochemical whole blood ketone sensor based on HCT compensation algorithm.
In this manuscript, we demonstrated an electrochemical test strip with HCT (hematocrit) compensation algorithm to improve the accuracy of blood ketone sensor. In the c...
A label-free biosensor based on graphene and reduced graphene oxide dual-layer for electrochemical determination of beta-amyloid biomarkers.
A label-free biosensor is developed for the determination of plasma-based Aβ1-42 biomarker in Alzheimer's disease (AD). The platform is based on highly conductive dual...
A compact SPR biosensor device for the rapid and efficient monitoring of gluten-free diet directly in human urine.
Celiac disease (CD) is a chronic autoimmune disorder induced in genetically susceptible individuals by the ingestion of gluten from wheat, rye, barley, or certain vari...
Development of an Aptamer Based Luminescent Optical Fiber Sensor for the Continuous Monitoring of Hg
A fluorescent optical fiber sensor for the detection of mercury (Hg2+) ions in aqueous solutions is presented in this work. The sensor was based on a fluorophore-label...
Ultrasensitive Stress Biomarker Detection Using Polypyrrole Nanotube Coupled to a Field-Effect Transistor.
Stress biomarkers such as hormones and neurotransmitters in bodily fluids can indicate an individual's physical and mental state, as well as influence their quality of...
Poly-
We have developed hydrogel nanoparticles made of poly-γ-glutamic acid (PGA) and chitosan, which entraps both glucose oxidase (GOx) and magnetic nanoparticles (MNPs) wi...
A photoluminescence biosensor for the detection of N-acyl homoserine lactone using cysteamine functionalized ZnO nanoparticles for the early diagnosis of urinary tract infections.
A urinary tract infection (UTI) is a recurrent infection that requires timely diagnosis and appropriate treatment. Conventional urinalysis methods are laborious and ti...
Highly Sensitive Photoelectrochemical Biosensor Based on Quantum Dots Sensitizing Bi
In this work, Bi2Te3 nanosheets treated with N-vinyl-pyrrolidinone showed highly sufficient and stable photocurrent for being used as a novel photoactive material. Acc...
Impedimetric Aptamer-Based Biosensors: Principles and Techniques.
Aptamers are a specific class of ligands with high affinities comparable to antibodies, which are selected and synthesized in vitro. In combination with impedance spec...
Development of Novel Magneto-Biosensor for Sulfapyridine Detection.
In this work, we report the development of a highly sensitive biosensor for sulfapyridine detection based on an integrated bio micro-electromechanical system (Bio-MEMS...
Folding-Based Electrochemical Aptasensor for the Determination of β-Lactoglobulin on Poly-L-Lysine Modified Graphite Electrodes.
Nowadays, food allergy is a very important health issue, causing adverse reactions of the immune system when exposed to different allergens present in food. Because of...
Synergistic interaction of diclofenac and its metabolites with selected antibiotics and amygdalin in wastewaters.
Diclofenac (DCF), a non-steroidal anti-inflammatory drug (NSAID) belongs to one of the most frequently detected pharmaceutical residues in the environment. Little is k...
Wearable Textile Supercapacitors for Self-Powered Enzyme-Free Smartsensors.
Wearable energy storage and flexible body biomolecule detection are two key factors for real-time monitoring of human health in a practical environment. It would be ra...
Mechanical Tolerance of Cascade Bioreactions via Adaptive Curvature Engineering for Epidermal Bioelectronics.
Epidermal bioelectronics that can monitor human health status non-invasively and in real time are core to wearable healthcare equipment. Achieving mechanically toleran...
Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition.
Sterols are crucial components of biological membranes, which are synthetized in the ER and accumulate in the plasma membrane (PM). Here, by applying a genetically enc...