2 条结果 关键词:电生理检测 ×

Development and initial testing of a novel slime mould biosensor.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2014 Whiting JG, de Lacy Costello B, Adamatzky A

全细胞生物传感器利用完整细胞或生物分子元件作为识别单元,将分析物刺激转化为可测信号。本文报道一种基于多头绒泡菌(Physarum polycephalum,PP)的新型全细胞生物传感器。作者测量PP暴露于多种化学物质时的电响应,并将响应量化为振荡频率与振幅的变化。该传感器能够检测所测试的化学物质,并可通过振荡频率或振幅的特定偏移区分...

Umami evaluation in taste epithelium on microelectrode array by extracellular electrophysiological recording.

Biochemical and biophysical research communications 2013 Zhang D, Zhang F, Zhang Q, Lu Y 等 6 人

鲜味是与甜、苦、酸、咸并列的基本味觉之一,常由氨基酸及其钠盐等小分子引发,可改善食品风味。本研究以完整味觉上皮作为生物传感元件,将其固定于60通道微电极阵列(MEA)表面,通过细胞外电生理记录评价鲜味刺激。实验采用磷酸盐缓冲液(PBS)维持组织活性,在37℃下分别给予L-谷氨酸(L-Glu)、L-天冬氨酸(L-Asp)、L-谷氨酸钠...