The development and validation of a sensitive, dual-flow cell, SPR-based biosensor immunoassay for the detection, semi-quantitation, and characterization of antibodies to darbepoetin alfa and epoetin alfa in human serum.

本研究开发并验证了一种基于表面等离子共振（SPR）的生物传感器免疫分析方法，用于检测、半定量和表征人血清中抗达比泊汀α（darbepoetin alfa）和抗促红素α（epoetin alfa）抗体。该双流通室分析采用Biacore 3000仪器，将epoetin alfa和darbepoetin alfa分别共价固定于羧甲基葡聚糖...