Wearable biosensor systems and resilience: a perfect storm in health care?
We begin by placing our discussion in the context of the chronic crisis in medical care, noting key features, including economic, safety and conceptual challenges. The...
Dissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humans.
UNLABELLED: Relatively little is known about the extent of the polyclonal antibody (PAb) repertoire elicited by herpes simplex virus (HSV) glycoproteins during natural...
Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery.
BACKGROUND: Transient receptor potential C3 (TRPC3) has been demonstrated to be involved in the regulation of vascular tone through endothelial cell (EC) hyperpolariza...
Construction of an uricase nanoparticles modified au electrode for amperometric determination of uric acid.
A method is described for preparation of uricase nanoparticles (100 nm in size) and their direct immobilization onto the Au electrode. The enzyme electrode along with ...
Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.
Hairpin polyamides (PAs) are an important class of sequence-specific DNA minor groove binders, and frequently employ a flexible motif, β-alanine (β), to reduce the mol...
Prussian blue-Au nanocomposites actuated hemin/G-quadruplexes catalysis for amplified detection of DNA, Hg2+ and adenosine triphosphate.
In this paper, horseradish peroxidase-mimicking DNAzyme (HRP-DNAzyme) and Prussian blue (PB)-gold (Au) nanocomposites were designed as versatile electrochemical sensin...
Amperometric determination of cadmium, lead, and mercury metal ions using a novel polymer immobilised horseradish peroxidase biosensor system.
This work was undertaken to develop a novel Pt/PANI-co-PDTDA/HRP biosensor system for environmental applications to investigate the inhibition studies by specific heav...
Methylamine-sensitive amperometric biosensor based on (His)6-tagged Hansenula polymorpha methylamine oxidase immobilized on the gold nanoparticles.
A novel methylamine-selective amperometric bienzyme biosensor based on recombinant primary amine oxidase isolated from the recombinant yeast strain Saccharomyces cerev...
Self-referenced spectroscopy using plasmon waveguide resonance biosensor.
A plasmon waveguide resonance (PWR) sensor is designed, fabricated, and tested for self-referenced biosensing. The PWR sensor is able to support two different polariza...
Trapping of a single DNA molecule using nanoplasmonic structures for biosensor applications.
Conventional optical trapping using a tightly focused beam is not suitable for trapping particles that are smaller than the diffraction limit because of the increasing...
Porous silicon Bloch surface and sub-surface wave structure for simultaneous detection of small and large molecules.
A porous silicon (PSi) Bloch surface wave (BSW) and Bloch sub-surface wave (BSSW) composite biosensor is designed and used for the size-selective detection of both sma...
Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding.
Fluorescent protein biosensors are typically implemented via genetic encoding which makes the examination of scarce cell samples impractical. By directly delivering th...
Highly sensitive assay for acetylcholinesterase activity and inhibition based on a specifically reactive photonic nanostructure.
Assays for acetylcholinesterase (AChE) with high sensitivity and high selectivity as well as facile manipulation have been urgently required in various fields. In this...
A portable DNAzyme-based optical biosensor for highly sensitive and selective detection of lead (II) in water sample.
A portable, rapid and cost-effective DNAzyme based sensor for lead ions detection in water samples has been developed using an optical fiber sensor platform. The prese...
A fluorescence glucose sensor based on pH induced conformational switch of i-motif DNA.
A facile fluorescence biosensor for the detection of glucose is proposed based on the pH-induced conformational switch of i-motif DNA in this paper. Glucose can be oxi...
Cytochrome P450 2D6 based electrochemical sensor for the determination of codeine.
Considering the enzymatic activity of the cytochrome P450 2D6 on substrates such as codeine, the current paper includes the development of an enzymatic biosensor for d...
Glucose biosensor based on multisegment nanowires exhibiting reversible magnetic control.
We describe the amperometric detection of glucose using oriented nanowires with magnetic switching of the bioelectrochemical process. The fabrication process of the na...
Self-assembled monolayers of mercaptobenzoic acid and magnetite nanoparticles as an efficient support for development of tuberculosis genosensor.
In this work, a genosensor for the electrochemical detection of genomic DNA from Mycobacterium tuberculosis was developed. The biosensor is based on self-assembled mon...
Ultrasensitive detection of cancer cells and glycan expression profiling based on a multivalent recognition and alkaline phosphatase-responsive electrogenerated chemiluminescence biosensor.
A multivalent recognition and alkaline phosphatase (ALP)-responsive electrogenerated chemiluminescence (ECL) biosensor for cancer cell detection and in situ evaluation...
In vitro selection, characterization, and biosensing application of high-affinity cylindrospermopsin-targeting aptamers.
Contamination of freshwater with cyanotoxin cylindrospermopsin (CYN) represents a significant global concern for public health. The sensitive detection of CYN is neces...