Potential applications of peptide nucleic acid in biomedical domain.
Peptide Nucleic Acid (PNA) are DNA/RNA synthetic analogs with 2-([2-aminoethyl] amino) acetic acid backbone. They partake unique antisense and antigene properties, jus...
Scalable COVID-19 Detection Enabled by Lab-on-Chip Biosensors.
INTRODUCTION: The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need for rapid, accurate, and point-of-care diagnostic testing. As of now, there is...
Three-dimensional biosensor surface based on novel thorns-like polyelectrolytes.
We have developed a new three-dimensional (3D) surface for use in biosensors that is based on modified novel thorns-like polyelectrolytes (3D-PETx), which comprises of...
A smartphone-based particle diffusometry platform for sub-attomolar detection of Vibrio cholerae in environmental water.
Each year, 3.4 million people die from waterborne diseases worldwide. Development of a rapid and portable platform for detecting and monitoring waterborne pathogens wo...
Protein based biomarkers for non-invasive Covid-19 detection.
COVID-19 has become a substantial lethal disease worldwide, and early diagnosis is a significant concern for this virus. Currently, RT-PCR is being used worldwide for ...
Diagnosis of scrub typhus: recent advancements and challenges.
Scrub typhus is a mite-borne, acute febrile illness caused by the bacterium Orientia tsutsugamushi. It is a re-emerging infectious disease of the tsutsugamushi triangl...
Graphene vs. silica coated refractory nitrides based core-shell nanoparticles for nanoplasmonic sensing.
Plasmonic nanoparticles based on conventional metals like gold (Au) and silver (Ag) has attracted significant attention of biosensor researchers. Core-shell nanopartic...
All-fiber all-optical quantitative polymerase chain reaction (qPCR).
Quantitative polymerase chain reaction (qPCR), the real-time amplification and measurement of a targeted DNA molecule, has revolutionized the biological sciences and i...
Plasmonic/magnetic molybdenum trioxide and graphitic carbon nitride quantum dots-based fluoroimmunosensing system for influenza virus.
A novel magnetic/plasmonic-assisted fluoro-immunoassay system is developed for the detection of influenza virus using magnetic-derivatized plasmonic molybdenum trioxid...
Antibody Immobilization in Zinc Oxide Thin Films as an Easy-Handle Strategy for
The antibody immobilization compatible with low-cost materials and label-free strategies is a challenge for biosensor device fabrication. In this study, ZnO thin film ...
Establishment and application of a multiple cross displacement amplification combined with nanoparticles-based biosensor method for the detection of Bordetella pertussis.
BACKGROUND: Bordetella pertussis is the causative agent of pertussis, a respiratory tract infectious disease. Efficient techniques for detection of B. pertussis isolat...
A Pterin-FAM-TAMRA Tri-color Fluorescence Biosensor to Detect the Level of KRAS Point Mutation.
Monitoring the changes in the level of KRAS point mutation (the concentration fraction of the KRAS point mutated DNA to the total DNA) in clinical treatment progress c...
A label-free lead(II) ion sensor based on surface plasmon resonance and DNAzyme-gold nanoparticle conjugates.
Detection of lead(II) (Pb2+) ions in water is important for the protection of human health and environment. The growing demand for onsite detection still faces challen...
Plasmonic biosensors relying on biomolecular conformational changes: Case of odorant binding proteins.
Plasmonic nanostructures serve in a range of analytical techniques that were developed for the analysis of chemical and biological species. Among others, they have bee...
Gravimetric biosensors.
Gravimetric transducers produce a signal based on a change in mass. These transducers can be used to construct gas sensors or biosensors using odorant binding proteins...
Mechanism of antibodies purification by protein A.
Protein A, a major cell wall component of Staphylococcus aureus, is one of the first immunoglobulin-binding proteins that is discovered about 80 years ago. However, a ...
Preparation of natural indicator incorporated media and its logical use as a colorimetric biosensor for rapid and sensitive detection of Methicillin-resistant Staphylococcus aureus.
Herein, we report a rational design in preparation of natural indicator incorporated media used as a rapid, selective, sensitive and economic colorimetric biosensor fo...
Organic electrochemical transistor for sensing of sialic acid in serum samples.
Sialic acid usually locates at the terminal of glycoproteins and glycolipids on cell surface. Compared to normal cells, cancer cells generally express much more sialic...
Screening and application of a truncated aptamer for high-sensitive fluorescent detection of metronidazole.
Aptamer-based biosensors have been widely constructed and applied to detect diverse targets. Metronidazole is a widely used broad-spectrum antibacterial drug, whose re...
A Probeless Capacitive Biosensor for Direct Detection of Amyloid Beta 1-42 in Human Serum Based on an Interdigitated Chain-Shaped Electrode.
Amyloid beta (aβ) 1-42, a peptide that is 1-42 amino acids long, is a major component of senile plaques in the brains of patients with Alzheimer's disease. Aβ detectio...